Suppr超能文献

儿童骶管阻滞时超声评估颅部扩散:不同剂量局部麻醉药的影响

Ultrasound assessment of cranial spread during caudal blockade in children: Effect of different volumes of local anesthetic.

作者信息

Sinha Chandni, Kumar Amarjeet, Sharma Shalini, Singh Akhilesh Kumar, Majumdar Somak, Kumar Ajeet, Sahay Nishant, Kumar Bindey, Bhadani U K

机构信息

Department of Anesthesia, AIIMS, Patna, India.

Department of Community and Family Medicine, AIIMS, Patna, India.

出版信息

Saudi J Anaesth. 2017 Oct-Dec;11(4):449-453. doi: 10.4103/sja.SJA_284_17.

Abstract

BACKGROUND

Ultrasound-guided caudal block injection is a simple, safe, and effective method of anesthesia/analgesia in pediatric patients. The volume of caudal drug required has always been a matter of debate.

MATERIALS AND METHODS

This present prospective, randomized, double-blinded study aimed to measure extent of the cranial spread of caudally administered levobupivacaine in Indian children by means of real-time ultrasonography. Ninety American Society of Anesthesiologists I/II children scheduled for urogenital surgeries were enrolled in this trial. Anesthesia and caudal analgesia were administered in a standardized manner in the patients. The patients received 0.5 ml/kg or 1 ml/kg or 1.25 ml/kg of 0.125% levobupivacaine according to the group allocated. Cranial spread of local anesthetic was noted using ultrasound.

RESULTS

There was no difference in the spread when related to age, sex, weight, or body mass index. A significant difference of ultrasound-assessed cranial spread of the local anesthetic was found between Group 1 (0.5 ml/kg) with both Group 2 (1 ml/kg) ( = 0.001) and with Group 3 (1.125 ml/kg) ( < 0.001) but there is no significant difference between Group 2 and Group 3 ( = 0.451) revealing that spinal level spread is only different between 0.5 ml/kg and 1 ml/kg of local anesthetic.

CONCLUSION

In conclusion, the ultrasound assessment of local anesthetic spread after a caudal block showed that cranial spread of the block is dependent on the volume injected into the caudal space. Since there was no difference between 1 ml/kg and 1.25 ml/kg, to achieve a dermatomal blockade up to thoracic level, we might have to increase the dose beyond 1.25 ml/kg, keeping the toxic dose in mind.

摘要

背景

超声引导下骶管阻滞注射是小儿患者麻醉/镇痛的一种简单、安全且有效的方法。所需骶管药物的剂量一直存在争议。

材料与方法

本前瞻性、随机、双盲研究旨在通过实时超声测量印度儿童骶管注射左旋布比卡因后的头端扩散范围。90例美国麻醉医师协会I/II级计划进行泌尿生殖系统手术的儿童纳入本试验。对患者进行标准化的麻醉和骶管镇痛。根据分组,患者接受0.125%左旋布比卡因0.5 ml/kg或1 ml/kg或1.25 ml/kg。使用超声记录局部麻醉药的头端扩散情况。

结果

在年龄、性别、体重或体重指数方面,扩散情况无差异。在第1组(0.5 ml/kg)与第2组(1 ml/kg)(P = 0.001)和第3组(1.125 ml/kg)(P < 0.001)之间,超声评估的局部麻醉药头端扩散存在显著差异,但第2组和第3组之间无显著差异(P = 0.451),这表明仅在0.5 ml/kg和1 ml/kg局部麻醉药时脊髓节段扩散不同。

结论

总之,骶管阻滞后局部麻醉药扩散的超声评估表明,阻滞的头端扩散取决于注入骶管间隙的剂量。由于1 ml/kg和1.25 ml/kg之间无差异,为达到直至胸段的皮节阻滞,我们可能必须将剂量增加至超过1.25 ml/kg,同时牢记中毒剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1375/5637423/8b8045cade42/SJA-11-449-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验