Zhu Miaojuan, Lin Shuaiyu, Chen Yifei, Yang Jiong, Nie Hanxiang
Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Department of Respiratory and Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Clin Respir J. 2025 Mar;19(3):e70055. doi: 10.1111/crj.70055.
Tuberculous pericarditis begins with fibrinous and hemorrhagic pericarditis, followed by pericardial effusion, then pericardial hypertrophy, which may turn into subacute or chronic stage, and partly develop into pericarditis. Early diagnosis and treatment have very important clinical significance.
We present a case of an 82-year-old man with a known history of hypertension who was admitted for pleural effusion. CT scan of the chest showed findings of pleural effusion. An echocardiographic study during admission revealed a small amount of pericardial effusion (~1.2 cm in thickness). A whole-body positron emission tomography-computer tomography (PET-CT) scan was then performed and showed a slightly increased fluorodeoxyglucose uptake in the entire pericardium considering tuberculosis. He was started on antituberculosis (TB) medications and tolerated them well. Follow-up echocardiographic study showed no re-accumulation of pleural effusion and pericardial fluid.
Transudative-exudative pleural effusion may be one of the clinical manifestations of tuberculous pericarditis. (1) Bilateral leaking pleural effusion may be the early clinical manifestation of tuberculous pericarditis; (2) PET/CT in the diagnosis and efficacy evaluation of tuberculous pericarditis is valuable; and (3) the central venous pressure may be an indicator of choice for treatment of tuberculous pericarditis.
结核性心包炎始于纤维蛋白性和出血性心包炎,继之出现心包积液,然后是心包肥厚,可发展为亚急性期或慢性期,部分发展为缩窄性心包炎。早期诊断和治疗具有非常重要的临床意义。
我们报告一例82岁男性,有高血压病史,因胸腔积液入院。胸部CT扫描显示胸腔积液表现。入院期间的超声心动图检查发现少量心包积液(厚度约1.2厘米)。随后进行了全身正电子发射断层扫描-计算机断层扫描(PET-CT),考虑为结核,显示整个心包的氟脱氧葡萄糖摄取略有增加。开始给予抗结核药物治疗,患者耐受性良好。随访超声心动图检查显示胸腔积液和心包积液未再积聚。
漏出-渗出性胸腔积液可能是结核性心包炎的临床表现之一。(1)双侧漏出性胸腔积液可能是结核性心包炎的早期临床表现;(2)PET/CT在结核性心包炎的诊断和疗效评估中有价值;(3)中心静脉压可能是结核性心包炎治疗的首选指标。