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非甾体抗炎药的自我药疗以及品牌药和非处方药的购买:秘鲁一项全国性调查分析

Self-medication with NSAIDs and purchase of branded and over-the-counter medicines: Analysis of a national survey in Peru.

作者信息

Benites-Meza Jerry K, Pinedo-Castillo Liseth, Cabanillas-Lazo Miguel, Boyd-Gamarra María A, Herrera-Añazco Percy, Mougenot Benoit, Benites-Zapata Vicente A

机构信息

Sociedad Científica de Estudiantes de Medicina de la Universidad Nacional de Trujillo, Trujillo, Peru.

Grupo Peruano de Investigación Epidemiológica, Unidad de Investigación para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola, Lima, Peru.

出版信息

J Public Health Res. 2025 Feb 25;14(1):22799036251319154. doi: 10.1177/22799036251319154. eCollection 2025 Jan.

Abstract

BACKGROUND

This study aimed to determine the association between self-medications with nonsteroidal anti-inflammatory drugs (NSAIDs) and the purchase of branded and over-the-counter medications in Peru.

DESIGN AND METHODS

This secondary analysis used a representative survey of Peru from 2014 to 2016. The exposure variable was self-medication with NSAIDs, defined as "the purchase of NSAIDs for oneself without a prescription." The outcome was the purchase of branded and over-the-counter medications. Crude prevalence ratios (cPR) and adjusted prevalence ratios (aPR) with their respective 95% confidence intervals (95% CI) were calculated.

RESULTS

Of the total of 2158 participants, 52.80% were women with an average age of 40.24 years. The prevalence of self-medication with NSAIDs was 68.21%, whereas the rates of purchasing branded and over-the-counter medications were 63.78% and 13.16%, respectively. The adjusted Poisson regression analysis showed an association between self-medication with NSAIDs and the purchase of branded (aPR = 1.18; 95% CI: 1.12-1.25;  < 0.001) and over-the-counter (aPR = 2.38; 95% CI: 1.95-2.90;  < 0.001) medications.

CONCLUSIONS

Approximately 7/10 users who self-medicate with NSAIDs chose branded medications, whereas nearly 1/5 opt for over-the-counter medications. Self-medication with NSAIDs was associated with a higher likelihood of purchasing branded and over-the-counter medications.

摘要

背景

本研究旨在确定秘鲁非甾体抗炎药(NSAIDs)的自我药疗与品牌药及非处方药购买之间的关联。

设计与方法

本二次分析使用了2014年至2016年秘鲁的一项代表性调查。暴露变量为NSAIDs的自我药疗,定义为“无处方自行购买NSAIDs”。结果是品牌药及非处方药的购买情况。计算了粗患病率比(cPR)和调整患病率比(aPR)及其各自的95%置信区间(95%CI)。

结果

在总共2158名参与者中,52.80%为女性,平均年龄40.24岁。NSAIDs自我药疗的患病率为68.21%,而购买品牌药和非处方药的比例分别为63.78%和13.16%。调整后的泊松回归分析显示,NSAIDs自我药疗与品牌药购买(aPR = 1.18;95%CI:1.12 - 1.25;P < 0.001)和非处方药购买(aPR = 2.38;95%CI:1.95 - 2.90;P < 0.001)之间存在关联。

结论

约十分之七使用NSAIDs进行自我药疗的用户选择品牌药,而近五分之一选择非处方药。NSAIDs自我药疗与购买品牌药和非处方药的可能性较高有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af3a/11863223/c75d037cc19c/10.1177_22799036251319154-fig1.jpg

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