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在一个大型中西部医疗系统中,地区贫困指数可预测新诊断高血压和2型糖尿病患者的年度慢性肾脏病筛查及慢性肾脏病发展:一项回顾性队列研究。

Area deprivation index predicts annual chronic kidney disease screening and chronic kidney disease development among patients with newly diagnosed hypertension and type 2 diabetes in a large midwestern health system: a retrospective cohort study.

作者信息

Ingle Mary, Khatib Rasha, Du Yuxian, Valuckaite Vesta, Singh Rakesh, Kong Sheldon, Williamson Todd, Baman Sarang

机构信息

Advocate Aurora Enterprises, Downers Grove, Illinois, USA.

Bayer United States of America, Whippany, New Jersey, USA.

出版信息

BMJ Public Health. 2024 Jun 3;2(1):e000679. doi: 10.1136/bmjph-2023-000679. eCollection 2024 Jun.

Abstract

BACKGROUND

We explore how area deprivation index (ADI), a national ranking of neighbourhood sociodemographic disadvantage is associated with chronic kidney disease (CKD) screening and development among patients with newly diagnosed hypertension (HTN) or type 2 diabetes (T2DM).

METHODS

Patients (n=235 208) with a new HTN or T2DM diagnosis between 2015 and 2018 in a large healthcare system were followed for 3 years to evaluate CKD screening (one estimated glomerular filtration rate and urinary albumin-to-creatine ratio) and CKD development. Multivariable logistic regression models evaluated associations between ADI quintiles with CKD screening and diagnosis.

RESULTS

Most patients were white (57%) females (55%) with HTN (65%). Few were screened in the first year after diagnosis (17%) and 9% developed CKD within 3 years. The odds of patients being screened were 54% greater (OR 1.54; 95% CI 1.48 to 1.60) and 146% greater (OR 2.46; 95% CI 2.19 to 2.76) for developing CKD for most deprived compared with the least deprived.

CONCLUSIONS

Patients with high ADI were more likely to be screened and almost twice as likely to develop CKD compared with the least deprived. Results highlight the importance of systematic health record data collection in large healthcare systems to evaluate social factors with health outcomes.

摘要

背景

我们探讨了地区贫困指数(ADI),一种邻里社会人口学劣势的全国排名,与新诊断的高血压(HTN)或2型糖尿病(T2DM)患者的慢性肾脏病(CKD)筛查及发病之间的关联。

方法

对2015年至2018年在一个大型医疗系统中首次诊断为HTN或T2DM的患者(n = 235208)进行了3年随访,以评估CKD筛查(一项估算肾小球滤过率和尿白蛋白与肌酐比值)及CKD发病情况。多变量逻辑回归模型评估了ADI五分位数与CKD筛查及诊断之间的关联。

结果

大多数患者为白人(57%)、女性(55%)且患有HTN(65%)。诊断后第一年很少有人接受筛查(17%),9%的患者在3年内发展为CKD。与最贫困者相比,最贫困者接受筛查的几率高出54%(OR 1.54;95% CI 1.48至1.60),发展为CKD的几率高出146%(OR 2.46;95% CI 2.19至2.76)。

结论

与最贫困者相比,高ADI患者接受筛查的可能性更大,发展为CKD的可能性几乎是其两倍。结果凸显了在大型医疗系统中系统收集健康记录数据以评估社会因素与健康结果之间关系的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c701/11816419/6148a54e5cff/bmjph-2-1-g001.jpg

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