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采用混合细胞设计的支架取栓器治疗前循环卒中:一项多中心注册研究

Thrombectomy for Anterior Circulation Stroke with a Hybrid Cell Design Stent Retriever: A Multicenter Registry.

作者信息

de Castro-Afonso Luís Henrique, Trivelato Felipe Padovani, Wajnberg Eduardo, Waihrich Eduardo Siqueira, Abud Thiago Giansante, Alves Saulo Villas Boas, Matsubara Anderson, Rezende Marco Tulio Salles, Araujo João Francisco Santoro, Nakiri Guilherme Seizem, Abud Daniel Giansante

机构信息

Division of Interventional Neuroradiology, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Division of Interventional Neuroradiology, Instituto Neurovascular, Hospital Felicio Rocho, Belo Horizonte, Minas Gerais, Brazil.

出版信息

J Neuroendovasc Ther. 2025;19(1). doi: 10.5797/jnet.oa.2024-0083. Epub 2024 Dec 17.

Abstract

OBJECTIVE

Thrombectomy is the standard recanalization treatment for acute ischemic stroke (AIS) due to large vessel occlusions (LVO). However, thrombectomy was validated using a few brands of devices. New types of thrombectomy devices have been developed, and assessing their safety and efficacy is essential. This study aimed to evaluate the safety and efficacy of thrombectomy with the Aperio Hybrid stent retriever (Acandis, Pforzheim, Germany) in the treatment of patients with AIS due to anterior circulation LVO.

METHODS

This was a multicenter registry of thrombectomy in the treatment of stroke due to anterior circulation LVO. Between January 2022 and January 2024, a total of 128 patients were included.

RESULTS

The mean procedure time was 62 minutes. The rates of the main outcomes were recanalization (extended treatment in cerebral ischemia 2b-3) 102/128 (79.7%), symptomatic intracranial hemorrhage 9/128 (7.0%), good clinical outcome (modified Rankin Scale = 0-2) 67/128 (52.3%), and mortality 24/128 (18.7%) at 3 months.

CONCLUSION

This study showed that, in a multicenter real-life scenario, the Aperio hybrid stent retriever was safe and effective for thrombectomy of anterior circulation strokes. The outcomes of this study were similar to those of previous large thrombectomy studies.

摘要

目的

血栓切除术是治疗因大血管闭塞(LVO)导致的急性缺血性卒中(AIS)的标准再通治疗方法。然而,血栓切除术仅通过少数几个品牌的器械得到验证。新型血栓切除器械已被研发出来,评估其安全性和有效性至关重要。本研究旨在评估使用Aperio Hybrid取栓支架(德国普福尔茨海姆的Acandis公司生产)对前循环LVO所致AIS患者进行血栓切除术的安全性和有效性。

方法

这是一项关于前循环LVO所致卒中血栓切除术的多中心登记研究。在2022年1月至2024年1月期间,共纳入128例患者。

结果

平均手术时间为62分钟。主要结局的发生率为再通(脑缺血扩展治疗2b - 3级)102/128(79.7%),症状性颅内出血9/128(7.0%),良好临床结局(改良Rankin量表评分 = 0 - 2)67/128(52.3%),3个月时死亡率24/128(18.7%)。

结论

本研究表明,在多中心真实临床场景中,Aperio Hybrid取栓支架对前循环卒中的血栓切除术安全有效。本研究结果与以往大型血栓切除术研究的结果相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d74/11864990/b7420d92d316/jnet-19-01-2024-0083-g001.jpg

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