Chu Zhongliang, Wang Rui, Zhou Tianyi
Department of Psychology, Faculty of Arts and Sciences, Center for Cognition and Neuroergonomics, State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Zhuhai, China.
State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.
Front Neurosci. 2025 Feb 13;19:1445006. doi: 10.3389/fnins.2025.1445006. eCollection 2025.
Vigilance refers to the ability to maintain alertness and sustain attention for prolonged periods to detect and respond to subtle changes in the environment. Previous research has explored the use of transcranial alternating current stimulation (tACS) to modulate brain oscillations and enhance vigilance/alertness. In this study, we explore the modulation effects of different stimulation parameters on Vigilance using an open-source dataset. The open-source dataset includes within participant application of High-Definition tES (HD-tES) types, targeting two cortical regions (frontal, motor) with one stimulation waveforms (30 Hz); combining human-participant high-density electroencephalography (EEG) with continuous behavioral metrics. We only analyzed the behavioral task performance data to assess how vigilant states are acutely altered by specific tES types. Our findings indicate that (1) Both online and offline tACS improve vigilance performance; (2) online tACS have greater effect on vigilance performance than offline tACS; (3) tACS that targeting frontal region have greater effect on vigilance performance than stimulating the motor region. These results align with the view of current the theoretical accounts on the oscillatory nature of vigilance attention and contribute to the groundwork for tACS closed-loop interventions for counteracting vigilance decrements.
警觉性是指长时间保持警觉并持续关注以检测和应对环境中细微变化的能力。先前的研究探讨了使用经颅交流电刺激（tACS）来调节脑振荡并提高警觉性/清醒度。在本研究中，我们使用一个开源数据集探索不同刺激参数对警觉性的调节作用。该开源数据集包括在参与者身上应用高清经颅电刺激（HD-tES）类型，以一种刺激波形（30Hz）靶向两个皮质区域（额叶、运动区）；将人类参与者的高密度脑电图（EEG）与连续行为指标相结合。我们仅分析行为任务表现数据，以评估特定tES类型如何急性改变警觉状态。我们的研究结果表明：（1）在线和离线tACS均能提高警觉性表现；（2）在线tACS对警觉性表现的影响大于离线tACS；（3）靶向额叶区域的tACS对警觉性表现的影响大于刺激运动区。这些结果与当前关于警觉性注意振荡本质的理论观点一致，并为tACS闭环干预以抵消警觉性下降奠定了基础。
