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开发用于识别急性头晕中前庭神经炎的诊断算法:流行病学、发病机制概述及基于证据的诊断方法指南

Developing a Diagnostic Algorithm for Identifying Vestibular Neuronitis in Acute Dizziness: An Overview of Epidemiology, Pathogenesis, and Evidence-Based Guidelines for Diagnostic Approaches.

作者信息

Vlastarakos Petros V, Sideris Giorgos, Vasileiou Eleni, Michailidou Efterpi, Papadimitriou Nikolaos, Palantzas Dimitrios, Melissourgou Konstantina, Panagoulis Evangelos, Gogoulos Panagiotis P, Nikolopoulos Thomas

机构信息

2nd ENT Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.

Otolaryngology - Head and Neck Surgery, Inselspital, University Hospital of Bern, Bern, CHE.

出版信息

Cureus. 2025 Jan 28;17(1):e78126. doi: 10.7759/cureus.78126. eCollection 2025 Jan.

DOI:10.7759/cureus.78126
PMID:40018481
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11866987/
Abstract

Vestibular neuronitis (VN) is a prevalent peripheral vestibular disorder presenting with sudden unilateral vestibular loss, leading to acute vertigo without associated cochlear or neurological symptoms. Diagnosis remains challenging due to symptom overlap with other vestibular and central disorders. This study reviews the epidemiology, pathogenesis, and diagnostic approaches for VN to propose a streamlined, evidence-based diagnostic algorithm. A comprehensive literature review was conducted, analyzing 114 studies, including randomized controlled trials, systematic reviews, and clinical guidelines. Emphasis is placed on the clinical history and bedside examinations, supported by ancillary tests to confirm the diagnosis and differentiate VN from central and other peripheral causes of vertigo. The proposed algorithm aims to enhance diagnostic precision and support clinical decision-making.

摘要

前庭神经炎(VN)是一种常见的外周前庭疾病,表现为突然单侧前庭功能丧失,导致急性眩晕,且无相关的耳蜗或神经症状。由于与其他前庭和中枢性疾病症状重叠,诊断仍然具有挑战性。本研究回顾了VN的流行病学、发病机制和诊断方法,以提出一种简化的、基于证据的诊断算法。进行了全面的文献综述,分析了114项研究,包括随机对照试验、系统评价和临床指南。重点在于临床病史和床边检查,并辅以辅助检查以确诊并将VN与中枢性及其他外周性眩晕原因相鉴别。所提出的算法旨在提高诊断准确性并支持临床决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d39/11866987/55e6b4ea7988/cureus-0017-00000078126-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d39/11866987/55e6b4ea7988/cureus-0017-00000078126-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d39/11866987/55e6b4ea7988/cureus-0017-00000078126-i01.jpg

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本文引用的文献

1
Cellular Processes Induced by HSV-1 Infections in Vestibular Neuritis.单纯疱疹病毒1型感染在前庭神经炎中诱导的细胞过程。
Viruses. 2023 Dec 20;16(1):12. doi: 10.3390/v16010012.
2
COVID-19 and Vestibular Symptoms and Assessment: A Review.新型冠状病毒肺炎与前庭症状及评估:综述
Audiol Neurootol. 2024;29(2):81-87. doi: 10.1159/000533448. Epub 2023 Sep 13.
3
Diagnostic and therapeutic strategies for vestibular neuritis of the Japan Society for Equilibrium Research.日本平衡研究学会的前庭神经炎诊断和治疗策略。
Auris Nasus Larynx. 2024 Feb;51(1):31-37. doi: 10.1016/j.anl.2022.12.005. Epub 2022 Dec 28.
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Diagnostic accuracy of neuroimaging in emergency department patients with acute vertigo or dizziness: A systematic review and meta-analysis for the guidelines for reasonable and appropriate care in the emergency department.急诊急性眩晕或头晕患者神经影像学诊断准确性的系统评价和荟萃分析:为急诊合理和适当护理制定的指南。
Acad Emerg Med. 2023 May;30(5):517-530. doi: 10.1111/acem.14561. Epub 2022 Aug 17.
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Acute unilateral vestibulopathy/vestibular neuritis: Diagnostic criteria.急性单侧前庭病变/前庭神经炎:诊断标准。
J Vestib Res. 2022;32(5):389-406. doi: 10.3233/VES-220201.
6
Vestibular function testing in the 21st century: video head impulse test, vestibular evoked myogenic potential, video nystagmography; which tests will provide answers?21世纪的前庭功能测试:视频头脉冲试验、前庭诱发肌源性电位、视频眼震图;哪些测试能给出答案?
Curr Opin Neurol. 2022 Feb 1;35(1):64-74. doi: 10.1097/WCO.0000000000001023.
7
Vascular mechanisms in acute unilateral peripheral vestibulopathy: a systematic review.急性单侧周围性前庭病变中的血管机制:一项系统评价
Acta Otorhinolaryngol Ital. 2021 Oct;41(5):401-409. doi: 10.14639/0392-100X-N1543.
8
Current diagnosis and treatment of vestibular neuritis: a narrative review.前庭神经炎的当前诊断与治疗:一篇叙述性综述
J Yeungnam Med Sci. 2022 Apr;39(2):81-88. doi: 10.12701/yujm.2021.01228. Epub 2021 Aug 9.
9
Capturing vertigo in the emergency room: three tools to double the rate of diagnosis.在急诊室捕捉眩晕:三种工具可将诊断率提高一倍。
J Neurol. 2022 Jan;269(1):294-306. doi: 10.1007/s00415-021-10627-1. Epub 2021 Aug 16.
10
Acute Vestibular Syndrome and ER Presentations of Dizziness.急性前庭综合征和头晕的急诊表现。
Otolaryngol Clin North Am. 2021 Oct;54(5):925-938. doi: 10.1016/j.otc.2021.05.013. Epub 2021 Jul 20.