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本文引用的文献

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Allergic contact dermatitis from pantolactone and dexpanthenol in wound healing creams.伤口愈合乳膏中泛内酯和右泛醇引起的变应性接触性皮炎。
Contact Dermatitis. 2022 Nov;87(5):468-471. doi: 10.1111/cod.14198. Epub 2022 Aug 17.
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Guidance on the renewal of the authorisation of feed additives.饲料添加剂授权续期指南。
EFSA J. 2021 Jan 7;19(1):e06340. doi: 10.2903/j.efsa.2021.6340. eCollection 2021 Jan.
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Calcium pantothenate is present in cosmetics and may cause allergic contact dermatitis.泛酸钙存在于化妆品中,可能会引起过敏性接触性皮炎。
Contact Dermatitis. 2021 Mar;84(3):201-203. doi: 10.1111/cod.13709. Epub 2020 Oct 20.
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Poult Sci. 2020 Sep;99(9):4436-4441. doi: 10.1016/j.psj.2020.05.021. Epub 2020 Jun 20.
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Allergic contact dermatitis caused dexpanthenol-But is that all?泛醇引起的过敏性接触性皮炎——但仅此而已吗?
Contact Dermatitis. 2019 Nov;81(5):391-392. doi: 10.1111/cod.13341. Epub 2019 Jul 11.
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Contact dermatitis caused by panthenol used for aftercare treatment of a new tattoo.
Contact Dermatitis. 2016 Jul;75(1):50-2. doi: 10.1111/cod.12544.
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Pustular irritant contact dermatitis caused by dexpanthenol in a child.一名儿童因泛醇引起的脓疱性刺激性接触性皮炎。
Cutan Ocul Toxicol. 2015 Mar;34(1):75-6. doi: 10.3109/15569527.2014.883405. Epub 2014 Feb 10.
8
Allergic contact dermatitis caused by panthenol in a child.一名儿童因泛醇引起的变应性接触性皮炎。
Contact Dermatitis. 2013 Nov;69(5):321-2. doi: 10.1111/cod.12116.
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Allergic contact dermatitis caused by dexpanthenol: report of two cases.
Contact Dermatitis. 2012 Mar;66(3):160-1. doi: 10.1111/j.1600-0536.2011.02005.x.

评估饲料添加剂泛酸钙和泛醇用于所有动物物种以更新其授权(帝斯曼营养产品有限公司)

Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd).

作者信息

Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, Galobart Jaume, Holczknecht Orsolya, Pizzo Fabiola, Radovnikovic Anita, Vettori Maria Vittoria, Amaduzzi Angelica

出版信息

EFSA J. 2025 Feb 27;23(2):e9252. doi: 10.2903/j.efsa.2025.9252. eCollection 2025 Feb.

DOI:10.2903/j.efsa.2025.9252
PMID:40018693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11865882/
Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of calcium d-pantothenate and d-panthenol for the renewal of its authorisation. Calcium d-pantothenate and d-panthenol are currently authorised as nutritional feed additives for all animal species and categories. The FEEDAP Panel concluded that the use of calcium d-pantothenate and d-panthenol as feed additive in animal nutrition under the conditions of use is of no concern for the safety of the target species, the consumer and the environment. Calcium d-pantothenate is not irritant to skin and eyes and is not a dermal sensitiser. d-panthenol is considered to be a skin and eye irritant and a dermal and respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of this renewal of the authorisation.

摘要

应欧盟委员会的要求,欧洲食品安全局(EFSA)被要求就泛酸钙和泛醇重新授权的安全性和有效性提供科学意见。泛酸钙和泛醇目前被批准作为所有动物种类和类别的营养饲料添加剂。饲料添加剂和动物营养产品专家委员会得出结论,在使用条件下,将泛酸钙和泛醇用作动物营养中的饲料添加剂对目标物种、消费者和环境的安全不构成关注。泛酸钙对皮肤和眼睛无刺激性,不是皮肤致敏剂。泛醇被认为是皮肤和眼睛刺激物以及皮肤和呼吸道致敏剂。在本次授权续期的背景下,无需评估该添加剂的有效性。