Götestam K G
Scand J Soc Med Suppl. 1977;14:141-5.
Bulk laxatives have been said to have a good effect in normalizing both hard and loose stools in geriatric patients as concluded from some open studies. In a double-blind study Vi-Siblin, Lunelax and placebo were compared in the six weeks treatment of 29 patients (8 patients on Vi-Siblin, 8 patients on Lunelax, 13 patients on placebo). Two weeks prior to the study and the two last weeks of the study defecation frequency, consistency of stools and the use of additional laxatives were registered by the personnel. Results showed no significant differences between groups or between substances. From this controlled double-blind study it is not possible to draw any definite conclusions regarding the efficacy of bulk laxatives on geriatric patients.
一些开放性研究得出结论称,容积性泻药据说在使老年患者的硬便和稀便恢复正常方面有良好效果。在一项双盲研究中,对29名患者(8名服用维 Siblin,8名服用鲁内拉克,13名服用安慰剂)进行了为期六周的治疗,比较了维 Siblin、鲁内拉克和安慰剂的效果。在研究前两周和研究的最后两周,工作人员记录了排便频率、粪便稠度以及额外泻药的使用情况。结果显示,各治疗组之间或各药物之间均无显著差异。从这项对照双盲研究中,无法就容积性泻药对老年患者的疗效得出任何明确结论。