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神经母细胞瘤的131I-间碘苄胍闪烁扫描术

131I-meta-iodobenzylguanidine scintigraphy of neuroblastomas.

作者信息

Munkner T

出版信息

Semin Nucl Med. 1985 Apr;15(2):154-60. doi: 10.1016/s0001-2998(85)80023-4.

Abstract

Sixteen neuroblastoma patients have been studied by 131I-meta-iodobenzylguanidine (MIBG) scintigraphy. Three patients were possibly cured, and their scintigraphy results were normal. Thirteen patients had tumors and metastases demonstrated by 131I-MIBG, two of these patients had a normal vanillylmandelic acid (VMA) excretion level. One patient has been treated by 131I-MIBG, but died. 131I-MIBG was concentrated in other cells too, eg, in erythrocytes and platelets.

摘要

对16例神经母细胞瘤患者进行了131I-间碘苄胍(MIBG)闪烁扫描研究。3例患者可能已治愈,其闪烁扫描结果正常。13例患者经131I-MIBG检查显示有肿瘤和转移灶,其中2例患者香草扁桃酸(VMA)排泄水平正常。1例患者接受了131I-MIBG治疗,但死亡。131I-MIBG也在其他细胞中浓聚,如红细胞和血小板。

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