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131I-间碘苄胍(MIBG)在神经母细胞瘤诊断中的临床应用。

The clinical use of 131I-meta-iodo-benzylguanidine (MIBG) for the diagnosis of neuroblastoma.

作者信息

Zagar I, Mitrović S, Adanja G, Maksimović L, Ivanovski P, Han R, Kovacić K

机构信息

Institute of Nuclear Medicine, University Clinical Centre, Belgrade.

出版信息

Med Pregl. 1993;46 Suppl 1:74-5.

PMID:8569615
Abstract

Whole-body scintigraphy with 131I-meta-iodo-benzylguanidine 131I-MIBG) was performed in 41 patients with neuroblastoma. In patients with clinical remission no pathological concentration of 131I-MIBG was found. In 30 patients with residual, recurrent or metastatic disease neuroblastoma was correctly localized by 131I-MIBG scintigraphy. It is concluded that 131I-MIBG whole-body scintigraphy is useful in the diagnosis and follow-up of neuroblastoma.

摘要

对41例神经母细胞瘤患者进行了131I-间碘苄胍(131I-MIBG)全身闪烁扫描。临床缓解的患者未发现131I-MIBG的病理性浓聚。在30例有残留、复发或转移性疾病的患者中,131I-MIBG闪烁扫描正确定位了神经母细胞瘤。结论是,131I-MIBG全身闪烁扫描对神经母细胞瘤的诊断和随访有用。

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