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[急性肺炎时血液白细胞酶活性细胞化学研究的重要性]

[Importance of the cytochemical study of blood leukocyte enzyme activity in acute pneumonias].

作者信息

Magomedov A Z

出版信息

Ter Arkh. 1985;57(3):130-3.

PMID:4002154
Abstract

The authors describe the results of cytochemical study of the activity of alkaline and acid phosphatase, myeloperoxidase and NADP-HH oxidase of neutrophils, acid phosphatase, succinate dehydrogenase and mitochondrial alpha-glycerophosphate dehydrogenases of peripheral blood lymphocytes in 90 patients with acute pneumonia on days 1, 3, 5, 7, 14 and 21 of the disease. It has been shown that changes in the activity of leukocytic enzymes are early and sensitive signs of acute inflammation in the lungs, reflecting the gravity and character of the disease. Some features of the enzymatic alterations depending on the degree of respiratory failure and allergic complications have been disclosed.

摘要

作者描述了对90例急性肺炎患者在疾病第1、3、5、7、14和21天中性粒细胞的碱性和酸性磷酸酶、髓过氧化物酶及NADP-HH氧化酶活性,以及外周血淋巴细胞的酸性磷酸酶、琥珀酸脱氢酶和线粒体α-甘油磷酸脱氢酶活性进行细胞化学研究的结果。结果表明,白细胞酶活性的变化是肺部急性炎症的早期敏感指标,反映了疾病的严重程度和特征。还揭示了酶活性改变的一些特点,这些特点取决于呼吸衰竭程度和过敏并发症情况。

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