Danilov I P, Makarevich A E
Ter Arkh. 1985;57(3):19-22.
In patients with chronic obstructive bronchitis, the rheological blood properties progressively deteriorate as the pulmonary insufficiency increases. These disorders are mainly caused by enhancement of red cell aggregation. The most remarkable disorders of the blood viscosity, e. g. the pathologically high viscosity syndrome, are recorded in patients with associated decompensated cor pulmonale and secondary erythrocytosis because of the hemoconcentration effect. Besides, the increase in the blood viscosity is dependent on the reduction in the propulsive capacity of the myocardium and acid-base unbalance. The role of the disorders of the blood viscosity in the pathogenesis of pulmonary hypertension is discussed.
在慢性阻塞性支气管炎患者中，随着肺功能不全的加重，血液流变学特性会逐渐恶化。这些紊乱主要是由红细胞聚集增强引起的。血液粘度最显著的紊乱，如病理性高粘度综合征，见于合并失代偿性肺心病和继发性红细胞增多症的患者，这是由于血液浓缩效应所致。此外，血液粘度的增加还取决于心肌推进能力的降低和酸碱失衡。本文讨论了血液粘度紊乱在肺动脉高压发病机制中的作用。
