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[镭疗转换为后装治疗的经验,特别提及空间剂量分布]

[Experience with the conversion from radium therapy to an afterloading procedure with special reference to spatial dose distribution].

作者信息

Frischkorn R

出版信息

Strahlentherapie. 1985 May;161(5):281-5.

PMID:4002252
Abstract

In radium therapy, the spatial and temporal dose distribution have never been identical in the different hospitals. However, the healing results did not vary correspondingly despite the partly great methodical differences between German and foreign hospitals. Furthermore, the spatial and temporal dose distribution in radium therapy did not conform to theoretic considerations but were a result of the low specific activity of radium as well as of the technical standard of X-ray therapy units until the sixties. It is shown that all requirements valid for radium therapy are also fulfilled by the afterloading method using a linear ray emitter, if an adequate dosage and fractionation is chosen. Taking into account the radiation risk, we think that the radium must be replaced by an afterloading method using a less dangerous nuclide. In our opinion the high dose rate technique is the most favorable method.

摘要

在镭疗法中,不同医院的空间和时间剂量分布从未完全相同。然而,尽管德国和国外医院在方法上存在部分巨大差异,但治疗效果并未相应地有所不同。此外,直到60年代,镭疗法的空间和时间剂量分布并不符合理论考量,而是镭的低比活度以及X射线治疗设备技术标准的结果。结果表明,如果选择适当的剂量和分次,使用线性射线发射器的后装方法也能满足对镭疗法的所有要求。考虑到辐射风险,我们认为必须用使用危险性较小的核素的后装方法来取代镭。我们认为高剂量率技术是最有利的方法。

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