Kikta D G, Devereaux M W, Chandar K
Stroke. 1985 May-Jun;16(3):510-2. doi: 10.1161/01.str.16.3.510.
We describe 2 patients with intracranial hemorrhage after ingestion of diet pills containing phenylpropanolamine (PPA) in combination with caffeine. The first patient had bilateral simultaneous intracerebral hemorrhages, and the second had a subarachnoid hemorrhage. PPA is widely used most often without prescription and causes intracranial hemorrhage more often than has been realized. The mechanism may be induction of a transient hypertensive crisis.
我们描述了2例在摄入含有苯丙醇胺（PPA）与咖啡因的减肥药后发生颅内出血的患者。第一例患者双侧同时发生脑出血，第二例患者发生蛛网膜下腔出血。PPA大多在无处方的情况下广泛使用，导致颅内出血的情况比人们意识到的更为常见。其机制可能是诱发短暂性高血压危象。
