Langewouters G J, Goedhard W J, Wesseling K H
Tijdschr Gerontol Geriatr. 1985 Apr;16(2):61-70.
This paper describes some results of our research on the viscoelastic properties of the human aorta. Pressure-diameter relations of 45 thoracic aortas, aged 30 to 88 years, were measured. The complex static measurement results were described by a model (formula) with three parameters. The dynamic (viscous) measurement results needed four parameters in a different model. De model parameters were next related to the age and the degree of sclerosis of the aortic segments. The results can be summarized as follows: the static properties change strongly with age; aortic compliance decreases substantially with aging; the dynamic (viscous) properties of the aorta do not change with age; although the degree of sclerosis of the aorta increased with age, we could not demonstrate a significant difference in the viscoelastic properties of 'normal' and sclerotic aortas. An explanation for the latter phenomenon was found in the dilation of the aorta which accompanies the increase of the degree of sclerosis and which serves as a hemodynamic compensation.
本文描述了我们对人体主动脉粘弹性特性研究的一些结果。测量了45个年龄在30至88岁之间的胸主动脉的压力-直径关系。复杂的静态测量结果由一个含三个参数的模型（公式）描述。动态（粘性）测量结果在一个不同的模型中需要四个参数。接下来将模型参数与主动脉段的年龄和硬化程度相关联。结果可总结如下：静态特性随年龄变化很大；主动脉顺应性随年龄增长大幅降低；主动脉的动态（粘性）特性不随年龄变化；尽管主动脉硬化程度随年龄增加，但我们未能证明“正常”和硬化主动脉的粘弹性特性存在显著差异。后一种现象的解释在于，随着硬化程度增加，主动脉会扩张，这起到了血液动力学补偿的作用。
