痤疮瘢痕和色素沉着的当前临床医生报告及患者报告结局指标评估：一项范围综述
An Assessment of Current Clinician- and Patient-Reported Outcome Measures for Acne Scarring and Dyspigmentation: A Scoping Review.
作者信息
Choe James, Urbonas Rebecca, Xia Eric, Yan Allison, Gaurav Ahana, Fladger Anne, Barbieri John S
机构信息
Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Schmidt College of Medicine, Florida Atlantic University, Boca Raton, Florida, USA.
出版信息
J Invest Dermatol. 2025 Feb 27. doi: 10.1016/j.jid.2025.02.135.
Acne-associated scarring and dyspigmentation (ie, erythema, hyperpigmentation) are common sequelae with significant psychosocial impact, but little is known about what measures are most often used to assess these outcomes. This scoping review evaluates the use of current patient-reported outcome measures (PROMs) and clinician-reported outcome measures (ClinROMs) for acne scars and dyspigmentation. For scars, 7 PROMs and 18 ClinROMs were used, with most being unvalidated. Similarly, for dyspigmentation, 4 PROMs and 8 ClinROMs were identified, but no validated PROMs were identified. These results highlight reliance on unvalidated measures in research and clinical trials and suggest the need for developing high-quality validated measures, particularly PROMs, to improve research quality and develop better treatments.
痤疮相关的瘢痕形成和色素沉着（即红斑、色素沉着过度）是常见的后遗症，具有重大的社会心理影响，但对于最常用于评估这些结果的措施知之甚少。本范围综述评估了当前患者报告结局测量指标（PROMs）和临床医生报告结局测量指标（ClinROMs）在痤疮瘢痕和色素沉着方面的应用。对于瘢痕，使用了7种PROMs和18种ClinROMs，其中大多数未经验证。同样，对于色素沉着，确定了4种PROMs和8种ClinROMs，但未发现经过验证的PROMs。这些结果凸显了在研究和临床试验中对未经验证的测量指标的依赖，并表明需要开发高质量的经过验证的测量指标，尤其是PROMs，以提高研究质量并开发出更好的治疗方法。
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