[接触毒死蜱的大鼠膈肌肌纤维的初始超微结构变化]
[Initial ultrastructural changes in the muscle fibers of the diaphragm in rats exposed to chlorophos].
作者信息
Kuznetsov V G, Tomilin N V, Cherniak T F, Mashanskiĭ V F
出版信息
Tsitologiia. 1985 Apr;27(4):411-4.
PMID:4002340
Abstract
Ultrastructural changes of rat diaphragm muscle fibers were studied after administration of chlorophos, i. e. organophosphorus inhibitor. Observations were made 10-180 seconds after treatment (concentrations--18 and 24 mM). The swelling of mitochondria and the increase in the length of sarcomeres were observed simultaneously. These changes were phasic. The swelling of mitochondria is probably due to the increase in energetical activity of muscle fibres.
摘要
在给予毒死蜱（即有机磷抑制剂）后，研究了大鼠膈肌肌纤维的超微结构变化。在处理后10 - 180秒进行观察（浓度为18和24 mM）。同时观察到线粒体肿胀和肌节长度增加。这些变化是阶段性的。线粒体肿胀可能是由于肌纤维能量活动增加所致。
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