烟酰胺腺嘌呤二核苷酸磷酸 - 癸醛加合物作为牛肉脑烟酰胺腺嘌呤二核苷酸磷酸连接的醛还原酶的抑制剂。
Nicotinamide adenine dinucleotide phosphate-decanaldehyde adduct as an inhibitor of beef brain NADP-linked aldehyde reductase.
作者信息
Towell J F, Erwin V G, Deitrich R A
出版信息
J Med Chem. 1979 Aug;22(8):1011-4. doi: 10.1021/jm00194a026.
PMID:40025
Abstract
The synthesis and characterization of the addition product of NADP and decanaldehyde are described. This adduct is an inhibitor of beef brain NADP-linked aldehyde reductase (Ki = 2.3 x 10(-6) M) along with the NADP adducts of butyraldehyde, phenylpropionaldehyde, and phenylacetaldehyde.
摘要
描述了NADP与癸醛加成产物的合成与表征。该加合物是牛肉脑NADP连接的醛还原酶的抑制剂（Ki = 2.3×10⁻⁶ M），丁醛、苯丙醛和苯乙醛的NADP加合物也是如此。
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