Levré E, Armani G, Caroli G
Quad Sclavo Diagn. 1979 Jun;15 Suppl 1:770-6.
Several antiseptic and disinfectant compounds have been investigated for their minimal inhibitory concentration (MIC) against antibiotic multiresistant strains of S. wien and S. bredeney as well as S. typhi and S. typhimurium strains characterized by wide spectrum of antibiotic sensitivity. The MICs of AgNO3, merthiolate, NaN3, phenol, Zephiran and Desogen were not substantially different for the former and the latter strains; on the contrary, the HgCl2 minimal inhibitory concentration was significantly higher against S. wien and S. bredeney than against the other strains. The mercury resistance appeared plasmid controlled and transferable to E. coli K-12, always associated with antibiotic resistance. The findings, which confirm the results of other AA., seem unrestrictive of the use of HgCl2, because its not probable selective role in the hospital environment.
已经研究了几种防腐剂和消毒剂化合物对维也纳沙门氏菌和布雷德尼沙门氏菌的抗生素多重耐药菌株以及具有广泛抗生素敏感性特征的伤寒沙门氏菌和鼠伤寒沙门氏菌菌株的最低抑菌浓度（MIC）。对于前一种和后一种菌株，硝酸银、硫柳汞、叠氮化钠、苯酚、洁尔灭和地索高氯铵的最低抑菌浓度没有实质性差异；相反，氯化汞对维也纳沙门氏菌和布雷德尼沙门氏菌的最低抑菌浓度明显高于对其他菌株的最低抑菌浓度。汞抗性似乎受质粒控制，并且可转移到大肠杆菌K-12，且总是与抗生素抗性相关。这些发现证实了其他研究的结果，似乎不限制氯化汞的使用，因为它在医院环境中不太可能具有选择性作用。
