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了解并绘制辅助生活设施中的抗生素处方及使用流程。

Understanding and mapping the antibiotic prescribing and administration process in assisted living facilities.

作者信息

Jacob Deepthi, Chewning Betty, Ford James H

机构信息

Social & Administrative Sciences Division, University of Wisconsin - Madison School of Pharmacy, Rennebohm Hall, 777 Highland Ave, Madison, WI 53705, USA.

出版信息

Explor Res Clin Soc Pharm. 2025 Feb 5;17:100572. doi: 10.1016/j.rcsop.2025.100572. eCollection 2025 Mar.

Abstract

OBJECTIVE

Inappropriate prescribing practices significantly contribute to antibiotic resistance which poses a significant public health challenge. While antibiotic prescribing and administration process has been widely studied in various settings including nursing homes, little is known about Assisted Living Facilities (ALFs). This study aims to map the antibiotic prescribing and administration processes in ALFs.

DESIGN

A qualitative descriptive study using the Systems Engineering Initiative for Patient Safety (SEIPS) 2.0 model.

METHODS

Seven semi-structured interviews were conducted with staff from five ALFs located in a mid-western state. Participating staff were either involved in or knowledgeable about the process. The interviews were analyzed in NVivo using SEIPS 2.0 model as a theoretical framework.

RESULTS

The analysis informed the mapping of a 33-step antibiotic prescribing and administration process for residents in ALFs. They were grouped into five sections: admission, resident having a change in condition, antibiotic prescribing, obtaining the prescription from the pharmacy, and antibiotic administration and follow-up. Pharmacies played critical role in delivery of prescriptions to ALFs and are uniquely positioned to support antibiotic stewardship efforts.

CONCLUSIONS AND IMPLICATIONS

This study is among the first to systematically map the antibiotic prescribing and administration process in ALFs. Insights gathered regarding the use of preferred pharmacies highlight opportunities for pharmacists in stewardship practices. Comparison of the process to that of nursing homes, suggests that several pharmacist-led stewardship interventions used there could be adapted effectively in ALFs. Further research is essential to assess the impact of antibiotic prescribing and pharmacist-driven stewardship interventions tailored specifically for ALFs.

摘要

目的

不恰当的处方行为显著促成了抗生素耐药性,这对公共卫生构成了重大挑战。虽然抗生素处方和给药过程已在包括疗养院在内的各种环境中得到广泛研究,但对于辅助生活设施(ALF)却知之甚少。本研究旨在梳理ALF中的抗生素处方和给药过程。

设计

一项使用患者安全系统工程倡议(SEIPS)2.0模型的定性描述性研究。

方法

对位于中西部一个州的五个ALF的工作人员进行了七次半结构化访谈。参与的工作人员要么参与了该过程,要么对该过程有所了解。访谈在NVivo中使用SEIPS 2.0模型作为理论框架进行分析。

结果

分析得出了ALF中居民33步抗生素处方和给药过程的流程图。它们被分为五个部分:入院、居民病情变化、抗生素处方、从药房获取处方以及抗生素给药和随访。药房在向ALF提供处方方面发挥着关键作用,并且在支持抗生素管理工作方面具有独特的地位。

结论与启示

本研究是首批系统梳理ALF中抗生素处方和给药过程的研究之一。关于使用首选药房所收集到的见解突出了药剂师在管理实践中的机会。将该过程与疗养院的过程进行比较表明,在疗养院使用的一些由药剂师主导的管理干预措施可以在ALF中有效采用。进一步的研究对于评估专门为ALF量身定制的抗生素处方和药剂师驱动的管理干预措施的影响至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78ff/11870267/1296318de9d1/gr1.jpg

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