Fan Jerry, Sanford Corry, Jones Billy Don
Department of Cardiology Baylor Scott & White Medical Center - Temple.
Department of Internal Medicine Baylor Scott & White Medical Center - Temple.
J Brown Hosp Med. 2023 Jul 1;2(3):81564. doi: 10.56305/001c.81564. eCollection 2023.
HACEK are gram negative organisms that are typically part of the oropharyngeal flora and are responsible for 1-3% of infective endocarditis cases. We describe an instance of multivalvular endocarditis caused by Aggregatibacter actinomycetemcomitans, which led to mechanical aortic valve dehiscence. Aggregatibacter actinomycetemcomitans represents approximately 20% of HACEK endocarditis cases and are exclusively found as part of normal oropharyngeal flora and break the vascular boundary during routine oral hygiene or plaque buildup. Antibiotics for 4-6 weeks with ceftriaxone is the mainstay of antibiotic therapy with surgical intervention reserved for those with valve dysfunction resulting in refractory heart failure.
HACEK是革兰氏阴性菌，通常是口咽菌群的一部分，占感染性心内膜炎病例的1%-3%。我们描述了一例由伴放线聚集杆菌引起的多瓣膜心内膜炎病例，该病例导致机械主动脉瓣裂开。伴放线聚集杆菌约占HACEK心内膜炎病例的20%，仅作为正常口咽菌群的一部分被发现，并在日常口腔卫生或牙菌斑形成过程中突破血管边界。以头孢曲松进行4-6周的抗生素治疗是抗生素治疗的主要方法，对于因瓣膜功能障碍导致难治性心力衰竭的患者则采用手术干预。
