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采用骨髓抽吸浓缩物进行股骨头缺血性坏死的髓芯减压术

Core Decompression With Bone Marrow Aspirate Concentrate for Avascular Necrosis of the Femoral Head.

作者信息

Carvalho Tiago, Souto Catarina, Rodrigues Nuno, Couto Roberto, Mesquita Montes José

机构信息

Orthopaedics, Unidade Local de Saúde da Póvoa de Varzim/Vila do Conde, Póvoa de Varzim, PRT.

出版信息

Cureus. 2025 Jan 29;17(1):e78187. doi: 10.7759/cureus.78187. eCollection 2025 Jan.

Abstract

INTRODUCTION

Avascular necrosis (AVN) of the femoral head is a complex and debilitating condition that predominantly affects a relatively young population. Core decompression of the femoral head is the primary surgical option for joint preservation, most commonly used in the early stages. However, clinical and radiological outcomes are variable in the literature. Biological therapies, such as bone marrow aspirate concentrate (BMAC), have also been used as adjuvants to complement this procedure. This study aims to evaluate the outcomes of this surgical intervention.

METHODS

From 2012 to 2022, we conducted a retrospective study at a small Portuguese National Health Service hospital of all patients who underwent core decompression combined with the use of BMAC. Clinical data were reviewed, and telephone interviews were conducted, with functional scores completed and radiological criteria assessed. The primary outcome was preservation of the native hip at two years postoperatively.

RESULTS

The series included 18 patients, totaling 24 affected hips. The average survival time after core decompression with BMAC was 14 months. The outcome was favorable in six (25%) hips, while 18 (75%) hips required a salvage arthroplasty. Patients with smaller preoperative lesions had more favorable outcomes than those with larger lesions.

CONCLUSION

The results of this study seem to confirm the importance of lesion size as a prognostic factor in the treatment of AVN lesions. Early stages alone do not guarantee surgical success.

摘要

引言

股骨头缺血性坏死(AVN)是一种复杂且使人衰弱的病症,主要影响相对年轻的人群。股骨头髓芯减压术是保留关节的主要手术选择,最常用于早期阶段。然而,文献中临床和影像学结果存在差异。生物疗法,如骨髓抽吸浓缩物(BMAC),也已被用作辅助手段来补充该手术。本研究旨在评估这种手术干预的结果。

方法

2012年至2022年,我们在一家小型葡萄牙国家卫生服务医院对所有接受髓芯减压联合使用BMAC的患者进行了一项回顾性研究。回顾了临床数据,并进行了电话访谈,完成了功能评分并评估了影像学标准。主要结局是术后两年保留天然髋关节。

结果

该系列包括18例患者,共24个患髋。采用BMAC进行髓芯减压后的平均生存时间为14个月。6个(25%)髋关节结局良好,而18个(75%)髋关节需要挽救性关节置换术。术前病变较小的患者比病变较大的患者结局更有利。

结论

本研究结果似乎证实了病变大小作为AVN病变治疗预后因素的重要性。仅早期阶段并不能保证手术成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4ed/11869797/4f2b739c19be/cureus-0017-00000078187-i01.jpg

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[Core decompression of the femoral head for avascular necrosis].股骨头缺血性坏死的髓芯减压术
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