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不明原因发热与丛集性头痛:一个新冠病毒难题

Fever of Unknown Origin and Cluster Headache: A COVID-19 Conundrum.

作者信息

Vysakha Kavadisseril Vivekanandan, Pillai Raina Thankappan, Cyriac Mathew, Sylaja P N, Aravind R

机构信息

Neurology GG hospital, Trivandrum, India.

Medicine GG hospital, Trivandrum, India.

出版信息

J Brown Hosp Med. 2023 Oct 1;2(4):88149. doi: 10.56305/001c.88149. eCollection 2023.

DOI:10.56305/001c.88149
PMID:40028302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11864441/
Abstract

We present a young girl with a family history of GPA who presented with fever of unknown origin and subsequently developed a secondary cluster headache. We hypothesize that the clinical manifestations are likely associated with hypothalamic dysregulation as a consequence of post-acute sequelae of COVID-19. Notably, the patient showed clinical improvement following the commencement of corticosteroid treatment.

摘要

我们报告了一名有肉芽肿性多血管炎(GPA)家族史的年轻女孩,她起初出现不明原因发热,随后发展为继发性丛集性头痛。我们推测,这些临床表现可能与新冠病毒病急性后遗症导致的下丘脑调节功能障碍有关。值得注意的是,患者在开始使用皮质类固醇治疗后临床症状有所改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d742/11864441/1eeecdd02e44/bhm_2023_2_4_88149_181628.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d742/11864441/1eeecdd02e44/bhm_2023_2_4_88149_181628.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d742/11864441/1eeecdd02e44/bhm_2023_2_4_88149_181628.jpg

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本文引用的文献

1
COVID-19 vaccination-triggered cluster headache episodes with frequent attacks.COVID-19 疫苗接种引发的集群性头痛发作频繁。
Cephalalgia. 2022 Nov;42(13):1420-1424. doi: 10.1177/03331024221113207. Epub 2022 Jul 13.
2
Substance P/ Neurokinin-1 Receptor, Trigeminal Ganglion, Latency, and Coronavirus Infection-Is There Any Link?P物质/神经激肽-1受体、三叉神经节、潜伏期与冠状病毒感染——有联系吗?
Front Med (Lausanne). 2021 Nov 18;8:727593. doi: 10.3389/fmed.2021.727593. eCollection 2021.
3
Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition.
国际头痛协会(IHS)头痛分类委员会《国际头痛疾病分类》第三版
Cephalalgia. 2018 Jan;38(1):1-211. doi: 10.1177/0333102417738202.
4
Increased risk of autoimmune disease in families with Wegener's granulomatosis.韦格纳肉芽肿病患者家族中自身免疫性疾病风险增加。
J Rheumatol. 2010 Dec;37(12):2553-8. doi: 10.3899/jrheum.091280. Epub 2010 Oct 1.