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在尼日利亚北部寻找失踪的结核病病例。

Finding missing TB cases in Northern Nigeria.

作者信息

Omotayo S A, Chukwuogo O, Ogbudebe C, Egbule D, Opara P, Bot T, Chukwu E, Nwadike P, Gordon I, Ezekhaigbe C, Yakubu A, Odume B

机构信息

KNCV Nigeria, Abuja, Nigeria.

RedAid, Enugu State, Nigeria.

出版信息

Public Health Action. 2025 Mar 1;15(1):38-43. doi: 10.5588/pha.24.0045. eCollection 2025 Mar.

DOI:10.5588/pha.24.0045
PMID:40028638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11841117/
Abstract

SETTING

Despite recent progress in TB notification rates, 6.2% of the 3.1 million 'missing' people with TB globally are from Nigeria. Identifying these 'missing' cases will improve TB control efforts in Nigeria.

OBJECTIVE

This paper aims to describe the outcome of an intensified TB case-finding strategy in northern Nigeria.

DESIGN

An intensified TB case-finding strategy was implemented in four states in northern Nigeria from October 2021 to September 2022. Trained ad-hoc staff screened hospital attendees and linked identified persons with presumptive TB to diagnosis using a hub and spoke approach. People with confirmed TB were linked to treatment. Contributions of the strategy to the national TB notification rates for each state were assessed.

RESULTS

A total of 1.17 million individuals were screened for TB across the four project States. 64,079 people with presumptive TB were identified, of which 10.1% were diagnosed with TB and 97% of those diagnosed were placed on treatment. Averagely, 33.3% of the TB cases notified from each state were contributions from the hospital-based Intensified TB case-finding intervention.

CONCLUSION

Facility-based intensified TB case-finding results in significant improvement in TB notification rates and a good strategy to improve the identification of missing TB cases in Nigeria.

摘要

背景

尽管最近结核病通报率有所提高,但全球310万“失踪”结核病患者中有6.2%来自尼日利亚。识别这些“失踪”病例将改善尼日利亚的结核病防控工作。

目的

本文旨在描述尼日利亚北部强化结核病病例发现策略的成果。

设计

2021年10月至2022年9月,在尼日利亚北部四个州实施了强化结核病病例发现策略。经过培训的临时工作人员对医院就诊者进行筛查,并采用“中心-辐条”模式将确诊为疑似结核病的人员转诊至诊断机构。确诊结核病的患者被转诊至治疗机构。评估了该策略对每个州国家结核病通报率的贡献。

结果

在四个项目州共对117万人进行了结核病筛查。共识别出64079名疑似结核病患者,其中10.1%被确诊为结核病,97%确诊患者接受了治疗。平均而言,每个州通报的结核病病例中有33.3%来自基于医院的强化结核病病例发现干预措施。

结论

基于医疗机构的强化结核病病例发现显著提高了结核病通报率,是改善尼日利亚“失踪”结核病病例识别的有效策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb84/11841117/b9c715a10d21/pha24-0045f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb84/11841117/b9c715a10d21/pha24-0045f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb84/11841117/b9c715a10d21/pha24-0045f1.jpg

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本文引用的文献

1
The TB Surge intervention: an optimized approach to TB case-finding in Nigeria.结核病激增干预措施:尼日利亚结核病病例发现的优化方法。
Public Health Action. 2023 Dec;13(4):136-141. doi: 10.5588/pha.23.0039. Epub 2023 Dec 7.
2
Facilitators and barriers to tuberculosis active case findings in low- and middle-income countries: a systematic review of qualitative research.中低收入国家结核病主动发现的促进因素和障碍:定性研究的系统评价。
BMC Infect Dis. 2023 Aug 7;23(1):515. doi: 10.1186/s12879-023-08502-7.
3
A Multi-Faceted Approach to Tuberculosis Active Case Finding among Remote Riverine Communities in Southern Nigeria.
多方位方法在尼日利亚南部偏远河流水域社区中发现结核病活动性病例。
Int J Environ Res Public Health. 2021 Sep 7;18(18):9424. doi: 10.3390/ijerph18189424.
4
The need to prioritise childhood tuberculosis case detection.优先开展儿童结核病病例检测的必要性。
Lancet. 2021 Apr 3;397(10281):1248-1249. doi: 10.1016/S0140-6736(21)00672-3. Epub 2021 Mar 23.
5
Treatment outcomes of drug susceptible Tuberculosis in private health facilities in Lagos, South-West Nigeria.尼日利亚拉各斯私营医疗机构中对药物敏感型肺结核的治疗效果。
PLoS One. 2021 Jan 20;16(1):e0244581. doi: 10.1371/journal.pone.0244581. eCollection 2021.
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Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.204 个国家和地区 1990-2019 年 369 种疾病和伤害导致的全球负担:2019 年全球疾病负担研究的系统分析。
Lancet. 2020 Oct 17;396(10258):1204-1222. doi: 10.1016/S0140-6736(20)30925-9.
7
Tuberculosis treatment outcomes: a fifteen-year retrospective study in Jos-North and Mangu, Plateau State, North - Central Nigeria.结核病治疗结果:尼日利亚中北部高原州乔斯北部和曼古地区的一项十五年回顾性研究。
BMC Public Health. 2020 Aug 11;20(1):1224. doi: 10.1186/s12889-020-09289-x.
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Analysis of alcohol policy in Nigeria: multi-sectoral action and the integration of the WHO "best-buy" interventions.尼日利亚的酒精政策分析:多部门行动和世卫组织“最佳购买”干预措施的整合。
BMC Public Health. 2019 Jun 24;19(1):810. doi: 10.1186/s12889-019-7139-9.
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Tuberculosis and gender - Factors influencing the risk of tuberculosis among men and women by age group.结核病与性别——按年龄组划分的影响男性和女性结核病风险的因素
Pulmonology. 2018 May-Jun;24(3):199-202. doi: 10.1016/j.pulmoe.2018.03.004.
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Framework Convention on Tobacco Control Implementation in Nigeria: Lessons for Low- and Middle-Income Countries.《尼日利亚实施烟草控制框架公约情况:对中低收入国家的启示》。
Nicotine Tob Res. 2019 Jul 17;21(8):1122-1130. doi: 10.1093/ntr/nty069.