Visible light-mediated decarboxylative allylic alkylation of Morita-Baylis-Hillman acetates with unactivated aliphatic acids.

Carboxylic acids are bench-stable and readily available chemical feedstocks that function as optimal and fundamental synthetic platforms for the construction of C(sp)-C(sp) bonds through decarboxylation processes. Herein, a visible light-induced and metal-free strategy for the direct decarboxylative allylic alkylation of Morita-Baylis-Hillman acetates with aliphatic acids was developed. The model delivered a series of trisubstituted alkenes in good to excellent yields. This protocol features broad substrate scope, and mild and redox-neutral conditions.