Zhang Hui, Yang Dan, Mei Yu-Tong, Guo Zi-Yi, Hou Qiu-Yao, Zheng Yu-Xuan, Jing Lin-Hai, Cheng De-Jun, Shi Ming-Song
Chemical Synthesis and Pollution Control Key Laboratory of Sichuan Province, College of Chemistry and Chemical Engineering, China West Normal University, Nanchong 637002, China.
Key Laboratory of Green Catalysis of Higher Education Institutes of Sichuan. College of Chemical Engineering Sichuan University of Science & Engineering, Zigong, 643000, China.
Org Biomol Chem. 2025 Mar 26;23(13):3102-3106. doi: 10.1039/d4ob02036g.
Carboxylic acids are bench-stable and readily available chemical feedstocks that function as optimal and fundamental synthetic platforms for the construction of C(sp)-C(sp) bonds through decarboxylation processes. Herein, a visible light-induced and metal-free strategy for the direct decarboxylative allylic alkylation of Morita-Baylis-Hillman acetates with aliphatic acids was developed. The model delivered a series of trisubstituted alkenes in good to excellent yields. This protocol features broad substrate scope, and mild and redox-neutral conditions.
