Suppr超能文献

排泄期计算机断层扫描对评估小儿重度肾外伤是否重要?

Is Excretory-Phase Computerized Tomography Important for Evaluation of Pediatric High-Grade Renal Trauma?

作者信息

Tong Ching Man Carmen, Shumaker Luke, Lucas Jacob, Bhatia Vinaya, Lee Albert, Abelson Benjamin, Crane Gabriella L, Ho Christina, Long Christopher J, Russell Robert T, Lovvorn Harold N, Wang Ming-Hsien, Weiss Dana A, Clayton Douglass B, Kitchens David M

机构信息

Department of Pediatric Urology, University of Alabama at Birmingham, Birmingham, Alabama.

Department of Pediatric Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

出版信息

J Urol. 2025 Jul;214(1):69-79. doi: 10.1097/JU.0000000000004515. Epub 2025 Mar 3.

Abstract

PURPOSE

There are no standardized guidelines for evaluation of pediatric renal trauma. We hypothesize that screening radiographic studies performed to rule out traumatic renal injuries in children can initially be evaluated by contrast-enhanced CT scans that lack an excretory phase.

MATERIALS AND METHODS

We retrospectively collected data from 5 pediatric trauma centers between 2007 and 2020. Patients younger than 18 years with American Association for the Surgery of Trauma grade 3 or higher renal trauma were included. Outcomes data included rate for delayed surgical or radiologic interventions, complications, or readmissions related to the initial renal injuries.

RESULTS

Three hundred fifty-one children were included. Thirty-six percent (127/351) had excretory-phase CT (EPCT) at initial evaluation. The median age was 13.6 (IQR, 9.1-16.3) years. Grade IV/V injury was present in 56.7% (72/127) of EPCT patients vs 53.6% (120/224) of patients with nonexcretory-phase CT (NEPCT;  = .3). Ninety-six percent (338/351) were blunt injuries. NEPCT patients had higher median injury severity scores (21 vs 16, < .01). EPCT children did not have more urinary drainage procedures (ureteral stent or percutaneous drain; 18% vs 12%, = .11). Patients with initial NEPCT did not experience longer hospital stay ( = .46), increased complications ( = .52), or readmissions ( = .54). Importantly, gross hematuria (GH) significantly predicted need for renal procedures (odds ratio = 2.06, 95% CI, 1.28-5.2, < .001).

CONCLUSIONS

Patients with initial NEPCT did not experience increased adverse outcomes or readmission. Those presenting with GH had increased risk of higher-grade renal injury and need for a renal procedure. This study suggests that high-grade pediatric renal trauma can be safely evaluated with NEPCT in initial trauma workup unless they present with GH.

摘要

目的

目前尚无评估小儿肾外伤的标准化指南。我们推测,用于排除儿童创伤性肾损伤的筛查影像学检查最初可通过缺乏排泄期的对比增强CT扫描进行评估。

材料与方法

我们回顾性收集了2007年至2020年间5家小儿创伤中心的数据。纳入年龄小于18岁、美国创伤外科学会分级为3级或更高的肾外伤患者。结果数据包括与初始肾损伤相关的延迟手术或放射学干预、并发症或再入院率。

结果

共纳入351名儿童。36%(127/351)在初始评估时进行了排泄期CT(EPCT)检查。中位年龄为13.6岁(四分位间距,9.1 - 16.3岁)。EPCT患者中IV/V级损伤的比例为56.7%(72/127),而非排泄期CT(NEPCT)患者中的这一比例为53.6%(120/224)(P = 0.3)。96%(338/351)为钝性损伤。NEPCT患者的中位损伤严重程度评分更高(21分对16分,P < 0.01)。EPCT患儿接受的尿液引流操作(输尿管支架或经皮引流)并不更多(18%对12%,P = 0.11)。初始NEPCT患者的住院时间并未延长(P = 0.46),并发症未增加(P = 0.52),再入院率也未增加(P = 0.54)。重要的是,肉眼血尿(GH)显著预测了肾脏手术的必要性(优势比 = 2.06,95%可信区间,1.28 - 5.2,P < 0.001)。

结论

初始NEPCT患者并未出现不良结局增加或再入院情况。出现GH的患者发生高级别肾损伤及需要进行肾脏手术的风险增加。本研究表明,在初始创伤评估中,除非患儿出现GH,否则使用NEPCT可安全地评估高级别小儿肾外伤。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验