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Myeloid neoplasms with MYC-positive double minutes: towards recognition as a distinct entity.

作者信息

Summerer Isolde, Walter Wencke, Meggendorfer Manja, Haferlach Torsten, Dicker Frank, Hutter Stephan, Nadarajah Niroshan, Stengel Anna, Kuehn Constanze, Kern Wolfgang, Bennett John M, Haferlach Claudia, Pohlkamp Christian

机构信息

MLL Munich Leukemia Laboratory, Munich, Germany.

University of Rochester Medical Center, Hematopathology Division, Department of Pathology, Rochester, NY, USA.

出版信息

Blood Cancer J. 2025 Mar 3;15(1):29. doi: 10.1038/s41408-025-01244-6.

DOI:10.1038/s41408-025-01244-6
PMID:40032819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11876648/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a266/11876648/e9c949743d26/41408_2025_1244_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a266/11876648/4e4c54cba43b/41408_2025_1244_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a266/11876648/e9c949743d26/41408_2025_1244_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a266/11876648/4e4c54cba43b/41408_2025_1244_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a266/11876648/e9c949743d26/41408_2025_1244_Fig2_HTML.jpg

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引用本文的文献

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本文引用的文献

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Interplay of TP53 allelic state, blast count, and complex karyotype on survival of patients with AML and MDS.TP53 等位基因状态、 blast 计数和复杂核型对 AML 和 MDS 患者生存的相互影响。
Blood Adv. 2023 Sep 26;7(18):5540-5548. doi: 10.1182/bloodadvances.2023010312.
2
AML classification in the year 2023: How to avoid a Babylonian confusion of languages.2023 年的 AML 分类：如何避免语言的巴别塔式混乱。
Leukemia. 2023 Jul;37(7):1413-1420. doi: 10.1038/s41375-023-01909-w. Epub 2023 Apr 29.
3
The diverse landscape of fusion transcripts in 25 different hematological entities.
Leuk Lymphoma. 2021 Dec;62(13):3292-3295. doi: 10.1080/10428194.2021.1953009. Epub 2021 Jul 20.
4
Genomic amplification of MYC as double minutes in a patient with APL-like leukemia.在一名急性早幼粒细胞白血病样白血病患者中，MYC基因以双微体形式出现基因组扩增。
Mol Cytogenet. 2014 Oct 22;7(1):67. doi: 10.1186/s13039-014-0067-6. eCollection 2014.
5
Rapid response to induction in a case of acute promyelocytic leukemia with MYC amplification on double minutes at diagnosis.诊断时伴有双微体上MYC扩增的急性早幼粒细胞白血病病例对诱导治疗的快速反应
Cancer Genet Cytogenet. 2010 Apr 15;198(2):170-2. doi: 10.1016/j.cancergencyto.2009.12.011.
6
Concomitant and successive amplifications of MYC in APL-like leukemia.在急性早幼粒细胞白血病样白血病中MYC的同时性和连续性扩增。
Cancer Genet Cytogenet. 2010 Feb;197(1):75-80. doi: 10.1016/j.cancergencyto.2009.11.001.
7
Deletion of MYC and presence of double minutes with MYC amplification in a morphologic acute promyelocytic leukemia-like case lacking RARA rearrangement: could early exclusion of double-minute chromosomes be a prognostic factor?在一例缺乏RARA重排的形态学急性早幼粒细胞白血病样病例中，MYC缺失及伴有MYC扩增的双微体的存在：早期排除双微体染色体是否可能是一个预后因素？
Cancer Genet Cytogenet. 2006 Apr 15;166(2):139-45. doi: 10.1016/j.cancergencyto.2005.10.013.
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MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene.血液系统恶性肿瘤中含MYC的双微体：支持附加体模型及排除MYC作为靶基因的证据
Hum Mol Genet. 2006 Mar 15;15(6):933-42. doi: 10.1093/hmg/ddl010. Epub 2006 Feb 1.
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Leukemia. 2002 Jan;16(1):53-9. doi: 10.1038/sj.leu.2402329.
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