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枕颈融合术后比寰枢椎融合术后有更多的术后并发症及翻修手术:一项回顾性多中心队列研究。

More postoperative complications and revision surgery after occipitocervical fusion than after atlantoaxial fusion: a retrospective multicenter cohort study.

作者信息

Uotani Koji, Flores Angel Oscar Paz, Tanaka Masato, Ekade Shashank J, Arataki Shinya, Komatsubara Tadashi, Oda Yoshiaki, Shinohara Kensuke, Ozaki Toshifumi

机构信息

Department of Orthopaedic Surgery, Okayama Rosai Hospital, Okayama, Japan.

Department of Orthopaedic Surgery, Okayama University Hospital, Okayama, Japan.

出版信息

Asian Spine J. 2025 Jun;19(3):444-451. doi: 10.31616/asj.2024.0374. Epub 2025 Mar 4.

Abstract

STUDY DESIGN

A retrospective multicenter cohort study.

PURPOSE

We sought to determine whether occipitocervical (OC) fusion is followed by more postoperative complications and revision surgery than is atlantoaxial (AA) fusion. We aim to compare postoperative complications and revision surgery associated with OC fusion and AA fusion.

OVERVIEW OF LITERATURE

OC and AA fusion are established techniques for restoring upper cervical stability. However, the outcomes of the two methods have not been compared.

METHODS

This study included 90 patients who underwent upper spinal fusion surgery for mechanical instability, performed by three surgeons in two hospitals from 2011 to 2023; OC fusion was indicated for irreducible AA subluxation, os odontoideum, and severe upper C1 fracture. Of the patients, 38 (mean age, 58.7 years) underwent OC fusion, and 52 (mean age, 62.8 years) underwent AA fusion. To evaluate surgical outcomes, we documented surgical time, intraoperative blood loss, postoperative complications, and the rate of revision surgery. Radiographs were obtained to identify screw malposition, rod breakage, and nonunion. To compare the outcomes of the two techniques, we used the Mann-Whitney U test for continuous variables and the chi-square or Fisher's exact test for dichotomous variables.

RESULTS

OC fusion took significantly longer (175.4 minutes) than AA fusion (150.7 minutes, p=0.020) and had a higher complication rate (39.5% vs. 11.5%, p <0.0001). The reoperation rate was 23.7% (9/38) after OC fusion and 3.8% (2/52) after AA fusion; the difference was statistically significant (p=0.0073). Average amounts of blood loss were 224 mL during OC fusion and 224 mL during AA fusion; the difference was not significant (p=0.947).

CONCLUSIONS

Although OC fusion is indispensable for certain conditions, particularly basilar invagination, it entails more risk than dose AA fusion; the choice of technique thus warrants careful consideration.

摘要

研究设计

一项回顾性多中心队列研究。

目的

我们试图确定与寰枢椎(AA)融合相比,枕颈(OC)融合术后是否会出现更多的并发症和翻修手术。我们旨在比较与OC融合和AA融合相关的术后并发症和翻修手术情况。

文献综述

OC和AA融合是恢复上颈椎稳定性的既定技术。然而,这两种方法的结果尚未进行比较。

方法

本研究纳入了90例因机械性不稳定接受上颈椎融合手术的患者,这些手术由两家医院的三位外科医生在2011年至2023年期间进行;OC融合适用于不可复位的AA半脱位、齿突小骨和严重的C1上骨折。其中,38例患者(平均年龄58.7岁)接受了OC融合,52例患者(平均年龄62.8岁)接受了AA融合。为了评估手术结果,我们记录了手术时间、术中出血量、术后并发症和翻修手术率。获取X线片以确定螺钉位置不当、棒材断裂和骨不连情况。为了比较两种技术的结果,我们对连续变量使用Mann-Whitney U检验,对二分变量使用卡方检验或Fisher精确检验。

结果

OC融合的手术时间(175.4分钟)明显长于AA融合(150.7分钟,p = 0.020),且并发症发生率更高(39.5%对11.5%,p < 0.0001)。OC融合后的再次手术率为23.7%(9/38),AA融合后的再次手术率为3.8%(2/52);差异具有统计学意义(p = 0.0073)。OC融合期间的平均出血量为224 mL,AA融合期间的平均出血量为224 mL;差异无统计学意义(p = 0.947)。

结论

尽管OC融合对于某些情况,特别是基底凹陷是必不可少的,但它比AA融合带来的风险更大;因此,技术的选择需要仔细考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e92/12242266/5e7097488c5f/asj-2024-0374f1.jpg

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