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中国一家三级医院孤立性男性尿道上裂的比较分析:隐匿型与非隐匿型病例

Comparative analysis of isolated male epispadias: concealed versus nonconcealed cases in a Chinese tertiary hospital.

作者信息

Li Jia-Yi, Yu Bo, Yang Meng-Cheng, Li Zong-Han, Song Hong-Cheng, Zhang Wei-Ping

机构信息

Department of Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.

Department of Pediatric Surgery, Bao'an Maternity and Child Health-care Hospital, Shenzhen 518102, China.

出版信息

Asian J Androl. 2025 Jul 1;27(4):502-507. doi: 10.4103/aja2024114. Epub 2025 Mar 4.

Abstract

Isolated male epispadias typically presents with preputial defects and dorsal urethral dehiscence. A less common subtype, known as concealed epispadias, is distinguished by an intact prepuce. Despite its clinical relevance, there is limited literature on this variant. In this study, we retrospectively analyzed the clinical data of 86 pediatric patients with isolated male epispadias treated in Beijing Children's Hospital (Beijing, China) from May 2004 to July 2023, including 19 cases of concealed epispadias and 67 of nonconcealed epispadias. We compared clinical characteristics, preoperative diagnostics, surgical techniques, postoperative outcomes, and sexual function during follow-up between the concealed and nonconcealed groups. No significant differences were observed between the two groups regarding surgical methods, postoperative complications, or rates of urinary incontinence. However, notable distinctions were found in the age at initial diagnosis, timing of surgery, frequency of incontinence, location of the urethral meatus, and postoperative urinary incontinence scores (all P < 0.05). Given the absence of penopubic epispadias in concealed cases, we categorized glans and penile epispadias within nonconcealed epispadias as distal epispadias ( n = 40) and subsequently compared them with concealed epispadias cases. The postoperative urinary incontinence scores did not differ significantly between the concealed and distal epispadias groups. These findings suggest that concealed epispadias represents a relatively milder form of the condition, characterized by the absence of penopubic involvement, lower rates of urinary incontinence, and favorable surgical outcomes. However, the intact prepuce in concealed cases underscores the need for careful identification and early diagnosis.

摘要

孤立性男性尿道上裂通常表现为包皮缺损和尿道背侧裂开。一种较罕见的亚型,称为隐匿性尿道上裂,其特征是包皮完整。尽管其具有临床相关性,但关于这种变异型的文献有限。在本研究中,我们回顾性分析了2004年5月至2023年7月在北京儿童医院(中国北京)接受治疗的86例孤立性男性尿道上裂患儿的临床资料,其中包括19例隐匿性尿道上裂和67例非隐匿性尿道上裂。我们比较了隐匿性和非隐匿性组之间的临床特征、术前诊断、手术技术、术后结果以及随访期间的性功能。两组在手术方法、术后并发症或尿失禁发生率方面未观察到显著差异。然而,在初次诊断年龄、手术时机、尿失禁频率、尿道口位置和术后尿失禁评分方面发现了显著差异(所有P<0.05)。鉴于隐匿性病例中不存在耻骨阴茎型尿道上裂,我们将非隐匿性尿道上裂中的龟头型和阴茎型尿道上裂归类为远端尿道上裂(n = 40),随后将它们与隐匿性尿道上裂病例进行比较。隐匿性和远端尿道上裂组术后尿失禁评分无显著差异。这些发现表明,隐匿性尿道上裂代表了一种相对较轻的病情形式,其特征是不存在耻骨部受累、尿失禁发生率较低且手术效果良好。然而,隐匿性病例中完整的包皮强调了仔细识别和早期诊断的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a777/12279356/fda82026eee8/AJA-27-502-g001.jpg

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