通过远程监测管理阻塞性睡眠呼吸暂停患者的持续气道正压通气随访：PROTEUS项目
Management of CPAP Follow-up by Telemonitoring in Obstructive Sleep Apnea: The PROTEUS Project.
作者信息
Drigo Riccardo, Ballarin Andrea, Menzella Francesco, Romagnoli Micaela, Salasnich Mauro, Marino Luigi, Lucernoni Paolo, Chizzolini Maddalena, Tondo Pasquale
机构信息
Department of Critical Care, Unit of Pulmonology, Montebelluna Hospital, Montebelluna, Italy.
Unit of Pulmonology, Ca' Foncello Hospital, Treviso, Italy.
出版信息
Nat Sci Sleep. 2025 Feb 27;17:357-363. doi: 10.2147/NSS.S501341. eCollection 2025.
PURPOSE
CPAP is the standard treatment for obstructive sleep apnea (OSA), but as many as 50% of patients discontinue its use, within three years. The PROTEUS project aims to enhance CPAP adherence through telemonitoring.
PATIENTS AND METHODS
OSA patients undergoing CPAP treatment since July 2018, had an in-person reassessment after three months, followed by quarterly telemonitoring by providers, who intervened in cases of poor adherence (less than 4 h·night or less than 70% of days), excessive mask leakage, or elevated residual apnea-hypopnea index (rAHI).
RESULTS
A total of 486 (~87%) out of 558 patients analyzed remained adherent to CPAP after five years. The average rAHI was 3.95 ± 5.25 events·h, the average CPAP usage was 6.35 ± 1.72 hours. Elevated mask leakage occurred in 25% of patients. No significant differences were found between sexes.
CONCLUSION
The PROTEUS project showed promising results in supporting long-term CPAP adherence. However, further research is needed to validate its long-term impact and wider applicability in OSA management.
目的
持续气道正压通气（CPAP）是阻塞性睡眠呼吸暂停（OSA）的标准治疗方法，但多达50%的患者在三年内停止使用。PROTEUS项目旨在通过远程监测提高CPAP的依从性。
患者与方法
自2018年7月起接受CPAP治疗的OSA患者，在三个月后进行了面对面重新评估，随后由医护人员进行季度远程监测，他们会对依从性差（每晚少于4小时或少于70%的天数）、面罩漏气过多或残余呼吸暂停低通气指数（rAHI）升高的情况进行干预。
结果
在分析的558例患者中，共有486例（约87%）在五年后仍坚持使用CPAP。平均rAHI为3.95±5.25次/小时，平均CPAP使用时间为6.35±1.72小时。25%的患者出现面罩漏气过多。性别之间未发现显著差异。
结论
PROTEUS项目在支持长期CPAP依从性方面显示出了有前景的结果。然而，需要进一步研究来验证其在OSA管理中的长期影响和更广泛的适用性。
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