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子痫。四、神经学检查结果及未来预后

Eclampsia. IV. Neurological findings and future outcome.

作者信息

Sibai B M, Spinnato J A, Watson D L, Lewis J A, Anderson G D

出版信息

Am J Obstet Gynecol. 1985 May 15;152(2):184-92. doi: 10.1016/s0002-9378(85)80020-x.

Abstract

Sixty-five patients with eclampsia were longitudinally evaluated regarding neurological abnormalities and maternal outcome (6 to 42 months) after eclampsia. Electroencephalograms were obtained on all patients during the subsequent 6 months. Computerized axial tomographic scans (n = 20) and cerebral arteriograms (n = 3) were obtained on patients with neurological deficits and/or those with an atypical clinical course. The electroencephalogram was abnormal in 49 patients (75%) at initial assessment but gradually returned to normal in all observed patients within 6 months. Cerebral arteriograms and computerized axial tomographic scans were normal in each patient studied. None of the patients had neurological deficits or subsequent convulsions on follow-up examination. Thirty-eight patients had one or more subsequent pregnancies without recurrent eclampsia, but 14 (37%) had pregnancy-induced hypertension. The findings suggest that neurological events of eclampsia are acute and transient and that long-term neurological deficit is rare in the properly managed patient. Computerized axial tomography and electroencephalography are rarely indicated in the management of such patients.

摘要

对65例子痫患者进行了纵向评估,观察子痫发作后(6至42个月)的神经功能异常和母亲结局。在随后的6个月内对所有患者进行了脑电图检查。对有神经功能缺损和/或临床病程不典型的患者进行了计算机断层扫描(n = 20)和脑血管造影(n = 3)。初始评估时,49例患者(75%)脑电图异常,但在6个月内所有观察患者的脑电图均逐渐恢复正常。所研究的每位患者的脑血管造影和计算机断层扫描均正常。随访检查中,无一例患者有神经功能缺损或随后发生惊厥。38例患者有一次或多次后续妊娠,无复发性子痫,但14例(37%)有妊娠高血压。研究结果表明,子痫的神经事件是急性和短暂的,在管理得当的患者中,长期神经功能缺损很少见。计算机断层扫描和脑电图检查在这类患者的管理中很少使用。

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