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计算机断层扫描肺动脉造影在肺血栓栓塞症诊断中的过度使用:“真实数据”

Overuse of Computed Tomography Pulmonary Angiography in the Diagnosis of Pulmonary Thromboembolism "Real-Life Data".

作者信息

Aksu Esra Arslan, Uzun Oğuz, Işıksungur İlkyaz, Gündoğdu Büşra Adıgüzel, Kökten Furkan Cem, Özbek Burak, Elmali Muzaffer

机构信息

Samsun University Faculty of Medicine, Department of Chest Medicine, Samsun, Turkiye.

Ondokuz Mayıs University Faculty of Medicine, Department of Chest Medicine, Samsun, Turkiye.

出版信息

Int J Gen Med. 2025 Feb 26;18:1103-1109. doi: 10.2147/IJGM.S499926. eCollection 2025.

Abstract

PURPOSE

Pulmonary thromboembolism (PTE) is a common cause of cardiovascular mortality with an increasing incidence rate. Scoring patients with suspected pulmonary thromboembolism according to their symptoms, findings, and risk factors is useful for empirical diagnosis and management. The combination of D-dimer and clinical scoring allows the diagnosis to be excluded in approximately 30% of patients with suspected PTE without the need for imaging methods. Despite this, clinical scores are not used effectively in the clinic. The aim of this study is to show that computed tomography pulmonary angiography (CTPA) is overused in real life and to emphasize that overuse of CTPA can be prevented with clinical tests.

PATIENTS AND METHODS

We studied 214 patients who underwent CTPA for suspected pulmonary thromboembolism. We evaluated whether clinical probability scoring (Wells scoring, Geneva scoring) was performed prior to CTPA from these patients' records and the health system database, and if so, the scores were evaluated. The rates and results of PERC criteria were also evaluated in patients.

RESULTS

Pulmonary thromboembolism was not detected on CTPA in 185 patients (86.4%). PERC criteria were not evaluated in all patients before CTPA. When the PERC criteria were evaluated by the study team, it was found that there was a significant relationship between PTE diagnosis and the criteria. There was also a significant correlation between Geneva score and CTPA results (p=0.000<0.05).

CONCLUSION

Preventing overuse of CTPA by evaluating clinical probability scores, PERC criteria and d-dimer levels is important in many ways. Prevention of overuse of CTPA use will reduce unnecessary workload in clinical functioning and provide financial gain. Although CTPA is a diagnostic method with high diagnostic accuracy in the diagnosis of PTE, it is overused in real life. The overuse of CTPA can be significantly reduced by the combined use of clinical probability scoring (Wells and Geneva), exclusion criteria (PERC) and d-dimer results.

摘要

目的

肺血栓栓塞症(PTE)是心血管疾病死亡的常见原因,发病率呈上升趋势。根据疑似肺血栓栓塞症患者的症状、检查结果和危险因素进行评分,有助于经验性诊断和管理。D-二聚体与临床评分相结合,可在约30%的疑似PTE患者中排除诊断,而无需使用影像学方法。尽管如此,临床评分在临床上并未得到有效应用。本研究的目的是表明在现实生活中计算机断层扫描肺动脉造影(CTPA)被过度使用,并强调通过临床检查可以防止CTPA的过度使用。

患者与方法

我们研究了214例因疑似肺血栓栓塞症接受CTPA检查的患者。我们从这些患者的病历和卫生系统数据库中评估CTPA检查前是否进行了临床概率评分(Wells评分、Geneva评分),如果进行了评分,则对评分进行评估。还评估了患者的PERC标准的发生率和结果。

结果

185例患者(86.4%)的CTPA检查未发现肺血栓栓塞症。并非所有患者在CTPA检查前都进行了PERC标准评估。当研究团队对PERC标准进行评估时,发现PTE诊断与该标准之间存在显著相关性。Geneva评分与CTPA结果之间也存在显著相关性(p = 0.000<0.05)。

结论

通过评估临床概率评分、PERC标准和D-二聚体水平来防止CTPA的过度使用在很多方面都很重要。防止CTPA的过度使用将减少临床工作中的不必要工作量并带来经济收益。虽然CTPA在PTE诊断中是一种诊断准确性高的诊断方法,但在现实生活中被过度使用。联合使用临床概率评分(Wells和Geneva)、排除标准(PERC)和D-二聚体结果可显著减少CTPA的过度使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c62/11873026/c95a4566f961/IJGM-18-1103-g0001.jpg

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