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纳米比亚奥希科托地区青少年中与抗逆转录病毒治疗不依从相关的因素。

Factors associated with non-adherence to antiretroviral therapy among adolescents in Oshikoto Region, Namibia.

作者信息

Ashipala Daniel O, Shuukwanyama Tukwatha A, Nghikevali Abraham V

机构信息

Department of General Nursing Sciences, Faculty of Health Sciences and Veterinary Medicine, University of Namibia, Rundu.

出版信息

S Afr Fam Pract (2004). 2025 Feb 28;67(1):e1-e9. doi: 10.4102/safp.v67i1.6020.

Abstract

BACKGROUND

In Namibia, the Omuthiya Antiretroviral Therapy (ART) Clinic has indicated that nine older adolescents (15-19 years) out of 125 adolescents active on ART have defaulted and become lost to care. This represents an 89% retention rate among older adolescents compared to a 97% retention rate for the adult population in the same facility. There is a lack of information on the extent of ART adherence among older adolescents, particularly in terms of viral suppression rates. This study aims to measure the level of adherence to ART treatment among adolescents enrolled at the Omuthiya ART Clinic in the Oshikoto Region, Namibia.

METHODS

From November to December 2020, a cross-sectional study was conducted among 100 adolescents living with HIV (ALHIV) at the Omuthiya ART Clinic. Data were collected through structured questionnaires and analysed using descriptive statistics and logistic regression.

RESULTS

The study found that 24% of adolescent patients on ART treated at the Omuthiya ART Clinic are non-adherent to treatment. A significant association found was between education level and adherence (p = 0.008), alcohol use and adherence (p = 0.022) and memory aids use and adherence (p  0.001).

CONCLUSION

Adolescents' adherence to ART at the Omuthiya ART Clinic is influenced by educational level, alcohol use, and memory aid use. Further research is needed to explore other potential factors influencing adherence.Contribution: These findings may be used to develop ongoing strategies and targeted interventions that prioritise a patient-centred care approach, recognising the autonomy of adolescents. In addition, they highlight the importance of a supportive family environment in managing HIV and improving ART adherence.

摘要

背景

在纳米比亚,奥穆蒂亚抗逆转录病毒疗法(ART)诊所指出,在125名接受抗逆转录病毒治疗的青少年中,有9名年龄较大的青少年(15 - 19岁)中断治疗并失去随访。与该机构中成年人群97%的留存率相比,这代表年龄较大青少年的留存率为89%。关于年龄较大青少年抗逆转录病毒治疗依从性的程度,尤其是病毒抑制率方面,缺乏相关信息。本研究旨在测量纳米比亚奥希科托地区奥穆蒂亚抗逆转录病毒疗法诊所登记的青少年中抗逆转录病毒治疗的依从水平。

方法

2020年11月至12月,对奥穆蒂亚抗逆转录病毒疗法诊所的100名感染艾滋病毒的青少年(ALHIV)进行了一项横断面研究。通过结构化问卷收集数据,并使用描述性统计和逻辑回归进行分析。

结果

研究发现,在奥穆蒂亚抗逆转录病毒疗法诊所接受抗逆转录病毒治疗的青少年患者中,有24%不坚持治疗。发现教育水平与依从性之间存在显著关联(p = 0.008)、饮酒与依从性之间存在显著关联(p = 0.022)以及使用记忆辅助工具与依从性之间存在显著关联(p = 0.001)。

结论

奥穆蒂亚抗逆转录病毒疗法诊所青少年对抗逆转录病毒治疗的依从性受教育水平、饮酒情况和记忆辅助工具使用的影响。需要进一步研究以探索影响依从性的其他潜在因素。贡献:这些发现可用于制定持续的策略和有针对性的干预措施,优先采用以患者为中心的护理方法,承认青少年的自主性。此外,它们强调了支持性家庭环境在管理艾滋病毒和提高抗逆转录病毒治疗依从性方面的重要性。

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