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印度尼西亚恙虫病的历史。

History of scrub typhus in Indonesia.

作者信息

Saraswati Kartika, Baird J Kevin, Blacksell Stuart D, Grijsen Marlous L, Day Nicholas P J

机构信息

Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, 10430 Jakarta, Indonesia.

Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 10400 Bangkok, Thailand.

出版信息

Trans R Soc Trop Med Hyg. 2025 Apr 1;119(4):338-345. doi: 10.1093/trstmh/traf017.

Abstract

Scrub typhus is a common but underrecognized cause of fever in the Asia-Pacific region. This review is the first to examine the history of scrub typhus in the context of notable historical events in Indonesia. Scrub typhus was first observed in 1902 and has since been documented through colonial and modern times. However, the available evidence is sparse. This lack of data is influenced by wider factors, including geopolitical climate and socio-economic factors. During the colonial era and World War II, research focused on economic and military interests. There were research gaps during the unstable period following independence in 1945. More research commenced only in the 1970s, mainly under the auspices of the Ministry of Health. Since 2000, there have been sporadic attempts to study scrub typhus on several major islands (Java, Sumatra, Sulawesi, Borneo, Bali). We found 51 relevant articles documenting the presence of the pathogen and its vectors, with only a single case confirmed with standard laboratory testing. This lack of data, combined with low awareness and diagnostic capacity, makes it difficult for policymakers to appreciate the impact of scrub typhus. Indonesia needs sustainable and continuous surveillance systems, infrastructure and research funding to ensure diseases of public health importance are not neglected.

摘要

恙虫病是亚太地区常见但未得到充分认识的发热病因。本综述首次在印度尼西亚重大历史事件的背景下审视恙虫病的历史。恙虫病于1902年首次被发现,此后在殖民时期和现代均有记载。然而,现有证据稀少。数据的缺乏受到更广泛因素的影响,包括地缘政治气候和社会经济因素。在殖民时代和第二次世界大战期间,研究集中在经济和军事利益方面。1945年独立后的不稳定时期存在研究空白。直到20世纪70年代才开始有更多研究,主要在卫生部的支持下进行。自2000年以来,在几个主要岛屿(爪哇、苏门答腊、苏拉威西、婆罗洲、巴厘岛)有零星的研究恙虫病的尝试。我们发现51篇相关文章记录了病原体及其传播媒介的存在,但只有一例通过标准实验室检测得到确诊。数据的缺乏,加上认识不足和诊断能力低下,使得政策制定者难以认识到恙虫病的影响。印度尼西亚需要可持续和持续的监测系统、基础设施和研究资金,以确保对具有公共卫生重要性的疾病不被忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2837/11960739/41c168096957/traf017fig1.jpg

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