Rezatofighi Azam, Soltani Majid, Latifi Seyed Mahmoud, Majdinasab Nastaran, Safari Zohre, Varmazyar Matin, Moradi Negin
Musculoskeletal Rehabilitation Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Department of Speech Therapy, Musculoskeletal Rehabilitation Research Center, School of Rehabilitation Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Dysphagia. 2025 Mar 4. doi: 10.1007/s00455-025-10811-9.
Multiple Sclerosis (MS) is a common chronic disease among young adults. It affects various aspects of Quality of Life (QOL). Dysphagia is a problem associated with neurological damage in MS patients. This study aimed to compare MS patients' QOL with and without dysphagia. This is a cross-sectional study performed on 40 patients with MS (20 with and 20 without dysphagia) selected from the MS Society members of Ahvaz, Iran. Research tools included the Persian version of Dysphagia in Multiple Sclerosis (DYMUS), Mini-Mental State Examination (MMSE), and Multiple Sclerosis Quality of Life-54 (MSQOL-54). The data were analyzed by SPSS software version 22 and the Mann-Whitney test. The results showed a significant difference in QOL score amongst patients with and without dysphagia. The QOL score of patients with dysphagia was significantly lower than patients without dysphagia. The main differences in the subscale of the QOL Index were mental component and physical activity. MS patients with dysphagia had lower QOL than patients without it. The results show that the quality of life of MS patients with dysphagia is lower than the quality of life of MS patients without dysphagia, and this issue includes different physical and mental aspects of the quality of life of these patients. According to the findings of this study, it seems that early referral of patients with MS to speech and language pathologists for the management of swallowing disorders in the early stages of the disease can be very important and help improve the wellbeing of these patients and their families.
多发性硬化症（MS）是年轻成年人中常见的慢性疾病。它会影响生活质量（QOL）的各个方面。吞咽困难是MS患者中与神经损伤相关的问题。本研究旨在比较有和没有吞咽困难的MS患者的生活质量。这是一项横断面研究，对从伊朗阿瓦士MS协会成员中选取的40例MS患者（20例有吞咽困难，20例无吞咽困难）进行。研究工具包括波斯语版的《多发性硬化症吞咽困难》（DYMUS）、简易精神状态检查表（MMSE）和多发性硬化症生活质量-54量表（MSQOL-54）。数据采用SPSS 22软件进行分析，并采用曼-惠特尼检验。结果显示，有和没有吞咽困难的患者在生活质量得分上存在显著差异。有吞咽困难的患者的生活质量得分显著低于没有吞咽困难的患者。生活质量指数子量表的主要差异在于心理成分和身体活动。有吞咽困难的MS患者的生活质量低于没有吞咽困难的患者。结果表明，有吞咽困难的MS患者的生活质量低于没有吞咽困难的MS患者，并且这个问题包括这些患者生活质量的不同身心方面。根据本研究的结果，似乎在疾病早期将MS患者尽早转诊给言语和语言病理学家以管理吞咽障碍可能非常重要，并有助于改善这些患者及其家人的健康状况。
