Phillips Angela N, Kirkland Lisa L, Wagner William E, Melamed Roman, Tierney David M
Department of Graduate Medical Education, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA.
Department of Critical Care, Abbott Northwestern Hospital, Allina Health, Minneapolis, MN, USA.
Case Rep Perinat Med. 2022 Aug 15;11(1):20220009. doi: 10.1515/crpm-2022-0009. eCollection 2022 Jan.
To describe the integration of point-of-care ultrasound (POCUS) and rotational thromboelastometry (ROTEM) in the diagnosis and management of cardiac arrest secondary to amniotic fluid embolism (AFE).
A 29-year-old female presented for induction of labor at 39 weeks. Labor was complicated by hemorrhage and subsequent sinus tachycardia pulseless electrical activity (PEA) arrest. Intra-arrest POCUS demonstrated right ventricular dilation and hypokinesis adding to a presumed hemorrhagic arrest etiology. Venoarterial extracorporeal membrane oxygenation (VA-ECMO) was initiated at the bedside following the POCUS findings. ROTEM further clarified the etiology of hemorrhage as disseminated intravascular coagulation (DIC), and in combination with the POCUS findings led to a final diagnosis of amniotic fluid embolism with DIC. The patient was maintained on VA-ECMO without heparin in the setting of DIC. She had a complicated hospital course but was discharged home with her healthy child and no residual physical or neurologic deficits.
In the absence of more specific testing modalities the utilization of rapidly available POCUS in conjunction with ROTEM can impact clinical decision making of cardiovascular resuscitation in patients during labor and delivery by narrowing the differential between pulmonary embolism and AFE.
描述床旁超声(POCUS)和旋转血栓弹力图(ROTEM)在羊水栓塞(AFE)继发心脏骤停的诊断和管理中的整合应用。
一名29岁女性在孕39周时前来引产。分娩过程中出现出血,随后发展为窦性心动过速伴无脉电活动(PEA)心脏骤停。心脏骤停期间的床旁超声显示右心室扩张和运动减弱,提示可能为出血性心脏骤停病因。根据床旁超声检查结果,在床边启动了静脉-动脉体外膜肺氧合(VA-ECMO)。ROTEM进一步明确出血病因是弥散性血管内凝血(DIC),结合床旁超声检查结果,最终诊断为羊水栓塞合并DIC。在DIC的情况下,患者在未使用肝素的情况下维持VA-ECMO治疗。她的住院过程复杂,但出院时带着健康的孩子,没有残留的身体或神经功能缺陷。
在缺乏更特异检测方法的情况下,快速可用的床旁超声与ROTEM联合使用,可通过缩小肺栓塞和AFE之间的鉴别诊断范围,影响分娩期患者心血管复苏的临床决策。