de Champs C, Demeocq F, Merle P, Palcoux J B, Morh M, Hartmann O
Arch Fr Pediatr. 1985 Feb;42(2):119-21.
A case of olfactory neuroblastoma in a 9 month-old girl is reported. Blindness and purulent meningitis were the first symptoms. Radiological examinations including CT scan revealed a sphenoidal tumor with penetration of the meninges. Surgery revealed an ethmoido-sphenoidal tumor mass extending into the pituitary fossea which consisted of malignant cells with the histological aspect of esthesioneuroblastoma. The rarity of this tumor in early childhood and its clinical polymorphism are emphasized.
报告了一例9个月大女孩患嗅神经母细胞瘤的病例。失明和化脓性脑膜炎是首发症状。包括CT扫描在内的影像学检查显示蝶骨肿瘤并侵犯脑膜。手术发现筛窦 - 蝶骨肿瘤肿块延伸至垂体窝,由具有嗅神经母细胞瘤组织学特征的恶性细胞组成。强调了这种肿瘤在儿童早期的罕见性及其临床多态性。