Toppet M, Vainsel M, Cantraine F, Franckson M
Arch Fr Pediatr. 1985 Feb;42(2):79-80.
In a population of 132 tuberculous children coming from immigrant families, statistical analysis of data showed a significant increase in serum alkaline phosphatase levels. This phenomenon is more significant when several antibiotics are used (Isoniazid and Rifampicin) than when monotherapy is used (Isoniazid). These results demonstrate a high tendency to occult osteomalacia in tuberculous patients treated by tuberculostatic drugs.
