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Leukemia inhibitory factor promotes growth and maintains stemness in giant panda MSCs.

作者信息

Li Feiping, Liu Yuliang, Zhang Mengshi, Wang Shenfei, Hu Xianbiao, Liu Xiangyu, Hou Rong, Cai Kailai

机构信息

Chengdu Research Base of Giant Panda Breeding, People's Republic of China, Chengdu, 610081, Sichuan, China.

Sichuan Key Laboratory of Conservation Biology On Endangered Wildlife, Sichuan, People's Republic of China, Chengdu, 610081, Sichuan, China.

出版信息

In Vitro Cell Dev Biol Anim. 2025 Mar;61(3):257-263. doi: 10.1007/s11626-025-01022-5. Epub 2025 Mar 5.

DOI:10.1007/s11626-025-01022-5
PMID:40045150
Abstract
摘要

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In Vitro Cell Dev Biol Anim. 2025 Mar;61(3):257-263. doi: 10.1007/s11626-025-01022-5. Epub 2025 Mar 5.
2
Basic Fibroblast Growth Factor Stimulates the Proliferation of Bone Marrow Mesenchymal Stem Cells in Giant Panda (Ailuropoda melanoleuca).碱性成纤维细胞生长因子刺激大熊猫（Ailuropoda melanoleuca）骨髓间充质干细胞的增殖。
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本文引用的文献

1
The protective effect of leukemia inhibitory factor on apoptosis of BMSCs induced by hypoxia and serum-deprivation.白血病抑制因子对缺氧和血清剥夺诱导的骨髓间充质干细胞凋亡的保护作用。
Am J Transl Res. 2023 Jun 15;15(6):4065-4078. eCollection 2023.
2
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration.白血病抑制因子调节许旺细胞增殖和迁移，影响周围神经再生。
Cell Death Dis. 2021 Apr 22;12(5):417. doi: 10.1038/s41419-021-03706-8.
3
Leukemia Inhibitory Factor (LIF) Overexpression Increases the Angiogenic Potential of Bone Marrow Mesenchymal Stem/Stromal Cells.
白血病抑制因子（LIF）过表达增强骨髓间充质干/基质细胞的血管生成潜能。
Front Cell Dev Biol. 2020 Aug 14;8:778. doi: 10.3389/fcell.2020.00778. eCollection 2020.
4
Developmental Stage-Dependent Effects of Leukemia Inhibitory Factor on Adipocyte Differentiation of Murine Bone Marrow Stromal Cells.白血病抑制因子对小鼠骨髓基质细胞脂肪细胞分化的发育阶段依赖性影响
Cell Biochem Biophys. 2016 Mar;74(1):11-7. doi: 10.1007/s12013-015-0703-8.
5
Characteristics of mesenchymal stem cells isolated from bone marrow of giant panda.大熊猫骨髓间充质干细胞的特征。
Stem Cells Dev. 2013 Sep 1;22(17):2394-401. doi: 10.1089/scd.2013.0102. Epub 2013 May 24.
6
Inhibition of MAP2K and GSK3 signaling promotes bovine blastocyst development and epiblast-associated expression of pluripotency factors.抑制 MAP2K 和 GSK3 信号通路可促进牛囊胚的发育，并促进多能性因子与上胚层相关的表达。
Biol Reprod. 2013 Mar 28;88(3):74. doi: 10.1095/biolreprod.112.103390. Print 2013 Mar.
7
LIF maintains progenitor phenotype of endothelial progenitor cells via Krüppel-like factor 4.LIF 通过 Krüppel 样因子 4 维持内皮祖细胞的祖细胞表型。
Microvasc Res. 2012 Nov;84(3):270-7. doi: 10.1016/j.mvr.2012.07.005. Epub 2012 Jul 23.
8
In vivo transplantation of bone marrow mesenchymal stem cells accelerates repair of injured gastric mucosa in rats.骨髓间充质干细胞体内移植加速大鼠损伤胃黏膜的修复。
Chin Med J (Engl). 2012 Mar;125(6):1169-74.
9
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone.从鼠密质骨中分离和培养间充质干细胞的方案。
Nat Protoc. 2010 Mar;5(3):550-60. doi: 10.1038/nprot.2009.238. Epub 2010 Feb 25.
10
Human multipotent stromal cells from bone marrow and microRNA: regulation of differentiation and leukemia inhibitory factor expression.来自骨髓的人多能基质细胞与微小RNA：分化调节及白血病抑制因子表达
Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18372-7. doi: 10.1073/pnas.0809807105. Epub 2008 Nov 14.