Miller April, Post Megan, Pellecchia Crescens, Bini John
General Surgery, Medical City Plano, Plano, TX, USA.
Trauma Surgery, Medical City Plano, Plano, TX, USA.
Trauma Case Rep. 2025 Feb 17;56:101142. doi: 10.1016/j.tcr.2025.101142. eCollection 2025 Apr.
Extracorporeal membrane oxygenation (ECMO) has been used for decades in patients where adequate oxygenation could not be achieved using traditional efforts. Data is emerging regarding its use in trauma. Retrospective data was collected from the ECMO database at an urban Level 1 trauma center between 2020 and 2024. Inclusion data was age > 17 years, trauma, and ECMO utilization during admission. Outcomes extracted included patient demographics, mechanism and type of injury, type of ECMO, ECMO days, hospital length of stay (LOS), intensive care LOS, date of injury to ECMO time, P/F ratio, ISS, complications, co-morbidities, anticoagulation, and mortality. Of the included 24 patients, 23 received veno-venous (VV) ECMO and one veno-arterial (VA) ECMO. The overall group demographics were: = 23 males vs. = 1 female, age 38.6 (±16.1) years. Duration of ECMO was 8.38 (±7.0) days, inpatient LOS 32.67 (±19.3) days, ICU LOS 26.33 (±18.0) days, DOI to initiation of ECMO 6.25 (±7.8). The ISS average was 29. The most common injury noted was rib fractures, average 4.6 (0-13) per patient. Other injuries included pneumothoraces (50 %), hemothoraces (35 %), blunt cardiac/sternal fracture (33 %). Complications on ECMO included transfusion requirement (54 %), DVT (13 %), and DIC (8 %). Of those studied, 87.5 % survived ECMO, with 70.8 % surviving to discharge. When using Mann-Whitney U and chi-square tests, there was not a statistically significant difference when comparing ISS, age, or P/F ratio between survivors versus non-survivors. Future research with increased sample size will be invaluable for the continued understanding of the role of ECMO in trauma.
体外膜肺氧合(ECMO)已在那些无法通过传统手段实现充分氧合的患者中使用了数十年。关于其在创伤治疗中的应用,相关数据正在不断涌现。我们从一家城市一级创伤中心的ECMO数据库中收集了2020年至2024年的回顾性数据。纳入数据包括年龄>17岁、创伤以及住院期间使用ECMO的情况。提取的结果包括患者人口统计学特征、损伤机制和类型、ECMO类型、ECMO使用天数、住院时长(LOS)、重症监护病房住院时长、受伤至开始使用ECMO的时间、P/F比值、损伤严重度评分(ISS)、并发症、合并症、抗凝情况以及死亡率。在纳入的24例患者中,23例接受了静脉 - 静脉(VV)ECMO,1例接受了静脉 - 动脉(VA)ECMO。总体人群的人口统计学特征为:男性 = 23例,女性 = 1例,年龄38.6(±16.1)岁。ECMO使用时长为8.38(±7.0)天,住院患者LOS为32.67(±19.3)天,重症监护病房LOS为26.33(±18.0)天,受伤至开始使用ECMO的时间为6.25(±7.8)天。ISS平均值为29。最常见的损伤是肋骨骨折,平均每位患者4.6根(0 - 13根)。其他损伤包括气胸(50%)、血胸(35%)、钝性心脏/胸骨骨折(33%)。ECMO相关并发症包括输血需求(54%)、深静脉血栓形成(DVT,13%)和弥散性血管内凝血(DIC,8%)。在研究对象中,87.5%的患者在ECMO治疗后存活,70.8%的患者存活至出院。当使用曼 - 惠特尼U检验和卡方检验时,比较存活者与非存活者的ISS、年龄或P/F比值时,未发现统计学上的显著差异。未来增加样本量的研究对于持续理解ECMO在创伤治疗中的作用将非常有价值。