Pandi Anandakumar, Chakraborty Balarko, Sen Nabendu, Kalappan Vanitha Manickam
Department of Biochemistry, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
Medical Research Unit, All India Institute of Medical Sciences, Deoghar, Jharkhand, India.
Arch Toxicol. 2025 May;99(5):2229-2234. doi: 10.1007/s00204-025-03996-3. Epub 2025 Mar 6.
Despite advancements in medicine, drug-induced liver injury continues to pose regulatory and clinical challenges. Ferulic acid, a naturally occurring polyphenol found in vegetables, fruits, and grains, has gained attention for its therapeutic properties. We report the hepatoprotective effects of ferulic acid against a range of pharmaceuticals and toxic compounds. Given the growing interest in natural hepatoprotective compounds, further research is essential to elucidate ferulic acid's role in liver protection.
尽管医学取得了进步，但药物性肝损伤仍然带来监管和临床方面的挑战。阿魏酸是一种存在于蔬菜、水果和谷物中的天然多酚，因其治疗特性而受到关注。我们报告了阿魏酸对一系列药物和有毒化合物的肝脏保护作用。鉴于对天然肝脏保护化合物的兴趣日益浓厚，进一步研究以阐明阿魏酸在肝脏保护中的作用至关重要。
