Eshaghi Shahri Mohammdad Mahdi, Noshirvani Nooshin, Kadivar Mahdi
Department of Food Science, College of Agriculture, Isfahan University of Technology, Isfahan, Iran.
Department of Food Science and Technology, Tuyserkan Faculty of Engineering & Natural Resources, Bu-Ali Sina University, Hamedan, Iran.
Int J Biol Macromol. 2025 May;306(Pt 4):141756. doi: 10.1016/j.ijbiomac.2025.141756. Epub 2025 Mar 4.
This study addresses the preparation and characterization of high performance multifunctional carboxymethyl cellulose (CMC) films loaded with zinc-based metal-organic frameworks (Zn-MOFs) and thyme essential oil (TEO). The effects of introducing Zn-MOFs and TEO on the morphological, mechanical, thermal, water barrier, optical, antioxidant, and antimicrobial properties of the films were systematically investigated. SEM results showed a uniform distribution of Zn-MOFs in the polymer matrix, which improved the tensile strength, water barrier, thermal stability, UV shielding, antimicrobial and antioxidant properties of films. The incorporation of 1, 2, and 3 % Zn-MOFs and 500 mL TEO into CMC-based films resulted in a significant increase in antioxidant activity by 38, 43, and 56 %, respectively. CMC-based films loaded with Zn-MOFs and TEO showed excellent antifungal activity against Penicillium digitatum and Aspergillus niger. These superior antioxidant and antimicrobial properties can be attributed to the high absorption effect of Zn-MOFs due to their high porosity and maintaining a high content of bioactive compounds in the film matrix. The films produced were proven to play a crucial role in controlling microbial growth, reducing weight loss and lowering the pH of soft cheese and ultimately extending its shelf life.
本研究涉及负载锌基金属有机框架（Zn-MOFs）和百里香精油（TEO）的高性能多功能羧甲基纤维素（CMC）薄膜的制备与表征。系统研究了引入Zn-MOFs和TEO对薄膜的形态、机械、热、阻水、光学、抗氧化和抗菌性能的影响。扫描电子显微镜（SEM）结果表明Zn-MOFs在聚合物基体中分布均匀，这提高了薄膜的拉伸强度、阻水性能、热稳定性、紫外线屏蔽性能、抗菌和抗氧化性能。在基于CMC的薄膜中加入1%、2%和3%的Zn-MOFs以及500 mL TEO，抗氧化活性分别显著提高了38%、43%和56%。负载Zn-MOFs和TEO的基于CMC的薄膜对指状青霉和黑曲霉表现出优异的抗真菌活性。这些优异的抗氧化和抗菌性能可归因于Zn-MOFs因其高孔隙率而具有的高吸附作用以及在薄膜基体中保持高含量的生物活性化合物。所制备的薄膜被证明在控制微生物生长、减少重量损失、降低软奶酪的pH值以及最终延长其保质期方面发挥着关键作用。
