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先天性心脏病患者心脏和大血管中血流速度增加。在无瓣膜狭窄情况下对其意义的评估。

Increased blood velocities in the heart and great vessels of patients with congenital heart disease. An assessment of their significance in the absence of valvar stenosis.

作者信息

Goldberg S J, Wilson N, Dickinson D F

出版信息

Br Heart J. 1985 Jun;53(6):640-4. doi: 10.1136/hrt.53.6.640.

DOI:10.1136/hrt.53.6.640
PMID:4005087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC481828/
Abstract

During a previous investigation and during routine clinical Doppler echocardiography velocities distal to normal valves were found to be increased in patients with congenital heart disease. To investigate this observation the velocity proximal and distal to cardiac valves was recorded in 56 patients with congenital heart disease. No detectable pressure gradient had been found across these valves at catheterisation and no velocity gradient greater than 20 cm/s was found across them by range gated Doppler echocardiography. In 82% of the patients, however, the blood velocity across one or more valves exceeded normal limits. Increased velocities were found at the tricuspid inflow (55%), pulmonary artery (38%), mitral inflow (34%), and ascending aorta (11%). Factors predisposing to the presence of increased velocities in these areas were increased flow through the valve and decreased compliance of the receiving chamber. This study shows the necessity for recording velocity both proximal and distal to a valve before a gradient is calculated according to the modified Bernouilli equation.

摘要

在先前的一项研究以及常规临床多普勒超声心动图检查中发现,先天性心脏病患者正常瓣膜远端的血流速度增加。为了研究这一现象,对56例先天性心脏病患者心脏瓣膜近端和远端的血流速度进行了记录。心导管检查未发现这些瓣膜存在可检测到的压力阶差,距离选通多普勒超声心动图也未发现其存在大于20 cm/s的速度阶差。然而,82%的患者中,一个或多个瓣膜处的血流速度超过正常范围。三尖瓣流入道(55%)、肺动脉(38%)、二尖瓣流入道(34%)和升主动脉(11%)处发现血流速度增加。这些区域血流速度增加的易感因素是通过瓣膜的血流量增加以及接受腔顺应性降低。本研究表明,在根据改良伯努利方程计算压力阶差之前,有必要记录瓣膜近端和远端的血流速度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2380/481828/45e467235f48/brheartj00114-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2380/481828/45e467235f48/brheartj00114-0058-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2380/481828/45e467235f48/brheartj00114-0058-a.jpg

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本文引用的文献

1
Noninvasive assessment and differentiation of left ventricular outflow obstruction with Doppler ultrasound.应用多普勒超声对左心室流出道梗阻进行无创评估与鉴别
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Verification and clinical demonstration of the echo Doppler series effect and vortex shed distance.回波多普勒系列效应及涡旋脱落距离的验证与临床演示。
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Doppler echocardiographic comparison of flows distal to the four cardiac valves.四个心脏瓣膜远端血流的多普勒超声心动图比较。
J Am Coll Cardiol. 1984 Aug;4(2):268-72. doi: 10.1016/s0735-1097(84)80212-0.
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Br Heart J. 1985 Apr;53(4):451-8. doi: 10.1136/hrt.53.4.451.
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Determination of pressure gradient in mitral stenosis with a non-invasive ultrasound Doppler technique.
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Diagnosis of ventricular septal defect by pulsed Doppler echocardiography. Sensitivity, specificity and limitations.经脉冲多普勒超声心动图诊断室间隔缺损。敏感性、特异性及局限性。
Circulation. 1978 Aug;58(2):322-6. doi: 10.1161/01.cir.58.2.322.