因膨体聚四氟乙烯带瓣肺动脉导管血栓形成继发慢性血栓栓塞性肺动脉高压而行肺动脉内膜剥脱术
Pulmonary Endarterectomy for Chronic Thromboembolic Pulmonary Hypertension Secondary to Expanded Polytetrafluoroethylene Valved Pulmonary Conduit Thrombosis.
作者信息
Robinson Eric, Logan Charles, Chiu Stephen, Husain Nazia, Cuttica Michael J, Mongé Michael C, Malaisrie S Christopher
机构信息
Division of Cardiac Surgery, Northwestern University Feinberg School of Medicine and Northwestern Medicine, Chicago, Illinois, USA.
Division of Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
出版信息
JACC Case Rep. 2025 Mar 5;30(5):103069. doi: 10.1016/j.jaccas.2024.103069.
BACKGROUND
There is no consensus on the preferred conduit for right ventricular outflow tract (RVOT) reconstruction for congenital cardiac disease.
CASE SUMMARY
We present a case of a 21-year-old woman with history of tetralogy of Fallot presenting with recurrent graft thrombosis and pulmonary emboli in the setting of RVOT reconstruction with a 20-mm expanded polytetrafluoroethylene (ePTFE) valved conduit (GORE PV1, W.L. Gore & Associates). A diagnosis of chronic thromboembolic pulmonary hypertension was made, and the patient underwent pulmonary endarterectomy and conduit exchange with a pulmonary homograft.
DISCUSSION
The novelty and clinical significance of this report lies in the confirmation of thrombosis of a large-diameter ePTFE valved pulmonary conduit (20 mm) and its implications for monitoring and need for further optimization of thromboprophylaxis strategies in this population.
背景
对于先天性心脏病右心室流出道（RVOT）重建的首选管道尚无共识。
病例摘要
我们报告一例21岁法洛四联症女性患者，在使用20毫米膨体聚四氟乙烯（ePTFE）带瓣管道（GORE PV1，W.L. Gore & Associates公司）进行RVOT重建的情况下，出现移植血管反复血栓形成和肺栓塞。诊断为慢性血栓栓塞性肺动脉高压，患者接受了肺动脉内膜剥脱术，并更换为同种异体肺动脉移植物。
讨论
本报告的新颖性和临床意义在于证实了大口径（20毫米）ePTFE带瓣肺动脉管道的血栓形成，及其对该人群监测的意义以及进一步优化血栓预防策略的必要性。
Zotero 插件