Yamada Shigeki
Department of Neurosurgery, Nagoya City University Graduate School of Medical Science, Kawasumi 1, Mizuho-cho, Mizuho-ku, Nagoya City, Aichi 467-8601, Japan.
Neurosurg Clin N Am. 2025 Apr;36(2):183-197. doi: 10.1016/j.nec.2024.11.007. Epub 2025 Jan 24.
Ventricle expansion and disproportionately enlarged subarachnoid-space hydrocephalus (DESH) are the hallmark features of idiopathic normal-pressure hydrocephalus, which has recently also been referred to as Hakim's disease. DESH refers to the unbalanced distribution of CSF in the subarachnoid space characterized by tightened sulci in the high convexities and Sylvian fissure dilation. The ventricles and Sylvian fissure expand in the parietal direction. This process compresses the brain and subarachnoid space around the parietal region. In addition to 2-dimensional imaging indicators, this study describes new 3-dimensional and 4-dimensional imaging indicators.
脑室扩张和不成比例的蛛网膜下腔扩大性脑积水（DESH）是特发性正常压力脑积水的标志性特征，该疾病最近也被称为哈基姆病。DESH是指脑脊液在蛛网膜下腔分布不均衡，其特征为大脑凸面脑沟变窄和大脑外侧裂扩张。脑室和大脑外侧裂在顶叶方向扩张。这一过程会压迫顶叶区域周围的脑和蛛网膜下腔。除了二维成像指标外，本研究还描述了新的三维和四维成像指标。
