Hentall I D
Brain Res. 1985 Jun 17;336(2):387-9. doi: 10.1016/0006-8993(85)90675-4.
An equation is developed for the membrane potential expected along a short, closed, straight, unbranched and unmyelinated fiber when a point source of steady current resides in the infinite, uniform, 3-dimensional medium. Most electrode placements induce a membrane potential whose absolute value is greater at terminals than midpoint--between 4.3 and 26.4 times greater in several arbitrary worked examples. Such natural phenomena as the effect of electric fields on the growth of nerve fibers could depend on this heightened susceptibility of terminals to external currents.
当一个稳定电流的点源存在于无限、均匀的三维介质中时,推导出了沿短的、封闭的、直的、无分支且无髓鞘纤维预期的膜电位方程。大多数电极放置所诱导的膜电位,其绝对值在纤维末端比中点处更大——在几个任意的实例计算中,前者比后者大4.3至26.4倍。电场对神经纤维生长的影响等自然现象可能取决于末端对外部电流这种更高的敏感性。