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神经纤维相互作用的数学研究。

A mathematical study of nerve fiber interaction.

作者信息

Clark J W, Plonsey R

出版信息

Biophys J. 1970 Oct;10(10):937-57. doi: 10.1016/S0006-3495(70)86344-5.

Abstract

This paper presents a quantitative description of the electric field interaction between two adjacent unmyelinated nerve fibers (one active, the other inactive) for the infinite medium and nerve trunk geometries, and considers their dependence on various electrical and geometrical parameters. Based on the use of synthetic giant axon data, the conclusion of this study is that the cross-sectional area of the nerve trunk and the specific resistivity of the interstitial medium are of particular importance to the degree of fiber interaction. Other factors such as separation distance between fibers, axoplasmic resistivity, membrane resistance, and capacitance of the inactive fiber, are also investigated and found to be of secondary importance.

摘要

本文给出了在无限介质和神经干几何结构中,两条相邻无髓神经纤维(一条处于活动状态,另一条处于非活动状态)之间电场相互作用的定量描述,并考虑了它们对各种电学和几何参数的依赖性。基于合成巨轴突数据的使用,本研究的结论是神经干的横截面积和间质介质的比电阻率对纤维相互作用的程度尤为重要。还研究了其他因素,如纤维间的分离距离、轴浆电阻率、膜电阻和非活动纤维的电容,发现它们的重要性次之。

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