Chirikos T N, Horner R D
Cancer. 1985 Jul 1;56(1):210-7. doi: 10.1002/1097-0142(19850701)56:1<210::aid-cncr2820560136>3.0.co;2-e.
This study investigates economic differentials in cancer survival in a sample of 1180 white men, focusing in particular on the relationship between income level and survivorship in the various subsites comprising the digestive system cancer category. Using the Cox proportional hazards model to control for confounding variables, the economic status-survivorship relationship is estimated for several subgroupings of primary malignancies. The results show significant variation in this relationship across different cancer sites, with a pronounced effect observed in carcinomas of the small intestine, peritoneum and, especially, colon and rectum. High-income patients with these malignancies had a significantly lower risk of dying from the disease (P less than 0.05) than either their middle- or lower-income counterparts, controlling for age, stage, and initial course of treatment. Differences in immunologic status, tumor characteristics, and follow-up treatment may account for these economic effects.
本研究调查了1180名白人男性样本中癌症生存方面的经济差异,特别关注收入水平与消化系统癌症类别中各个亚部位的生存率之间的关系。使用Cox比例风险模型控制混杂变量,对几种原发性恶性肿瘤亚组的经济状况-生存关系进行了估计。结果显示,这种关系在不同癌症部位存在显著差异,在小肠癌、腹膜癌,尤其是结肠癌和直肠癌中观察到明显影响。在控制年龄、分期和初始治疗过程后,患有这些恶性肿瘤的高收入患者死于该疾病的风险显著低于中等收入或低收入患者(P小于0.05)。免疫状态、肿瘤特征和后续治疗的差异可能是造成这些经济影响的原因。