Oosterhuis J W, Lung P F, Verschueren R C, Oldhoff J
Cancer. 1985 Jul 15;56(2):368-70. doi: 10.1002/1097-0142(19850715)56:2<368::aid-cncr2820560227>3.0.co;2-4.
The Cavitron Ultrasonic Surgical Aspirator (CUSA) (Cooper Medical, Stamford, CT) is a relatively new surgical modality. The risk of tumor seeding during tumor surgery has not been studied until now. Hanks balanced salt solution, normal saline, distilled water, and Dakin's solution were used as irrigation fluids during CUSA fragmentation of Lewis lung carcinoma in C57B1/10 female mice, using the machine at 40% of its maximal output. All four irrigation fluids contained viable tumor cells--growing in vitro as well as in vivo--after tumor aspiration. Normal saline was also used when the machine was operating at its maximal output. Under these conditions, the irrigation fluid contained viable tumor cells as well.
卡维特龙超声手术吸引器（CUSA）（库珀医疗公司，斯坦福德，康涅狄格州）是一种相对较新的手术方式。迄今为止，尚未对肿瘤手术期间肿瘤种植的风险进行研究。在C57B1/10雌性小鼠的Lewis肺癌CUSA破碎过程中，使用汉克斯平衡盐溶液、生理盐水、蒸馏水和达金溶液作为冲洗液，机器以其最大输出功率的40%运行。在肿瘤抽吸后，所有四种冲洗液中都含有可存活的肿瘤细胞——在体外和体内均可生长。当机器以最大输出功率运行时也使用生理盐水。在这些条件下，冲洗液中也含有可存活的肿瘤细胞。
